Oxidative damage and mitochondrial health

A well-written article relating mitochondrial health to the use of antioxidants and can be found here.  Mitochondria are particularly susceptible to oxidative damage and such damage is implicated in many debilitating conditions including  cardiovascular disease, stroke, Parkinson’s disease, Alzheimer’s disease, fibromyalgia, schizophrenia, dementia, bipolar disorder, epilepsy, retinitis pigmentosa, and diabetes mellitus.  I continue to strongly believe that there is a central role for anti-oxidants in an effective longevity regimen.  Specifically, Co Q-10. Alpha-lipoic acid and acytl-l-carnitine are important antioxidants for maintaining the health of mitochondria.  An additional report came to my attention today confirming how the use of antioxidants can  support mitochondrial health, this one originated at the Stanford School of Medicine. Blood samples from 20 patients with various mitochondrial diseases uniformly showed depleted glutathione, indicating a lowering of those patients’ antioxidant defenses.  Apparently, mitochondrial disorders generate large numbers of free radicals.  On the other hand, those patients taking antioxidant supplements did not have depleted glutathione, they found, indicating stronger antioxidant defenses.

About Vince Giuliano

Being a follower, connoisseur, and interpreter of longevity research is my latest career. I have been at this part-time for well over a decade, and in 2007 this became my mainline activity. In earlier reincarnations of my career. I was founding dean of a graduate school and a university professor at the State University of New York, a senior consultant working in a variety of fields at Arthur D. Little, Inc., Chief Scientist and C00 of Mirror Systems, a software company, and an international Internet consultant. I got off the ground with one of the earliest PhD's from Harvard in a field later to become known as computer science. Because there was no academic field of computer science at the time, to get through I had to qualify myself in hard sciences, so my studies focused heavily on quantum physics. In various ways I contributed to the Computer Revolution starting in the 1950s and the Internet Revolution starting in the late 1980s. I am now engaged in doing the same for The Longevity Revolution. I have published something like 200 books and papers as well as over 430 substantive.entries in this blog, and have enjoyed various periods of notoriety. If you do a Google search on Vincent E. Giuliano, most if not all of the entries on the first few pages that come up will be ones relating to me. I have a general writings site at www.vincegiuliano.com and an extensive site of my art at www.giulianoart.com. Please note that I have recently changed my mailbox to vegiuliano@agingsciences.com.
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