Monthly Archives: April 2009

Another cross-species pathway has been discovered that allows interventions to lengthen life in primitive organisms, C. elegans nematode worms in this case.  The pathway is related to the hypoxic response, how cells respond to protect themselves when there is insufficient … Continue reading →

The conventional wisdom has been that cell division in heart muscle cells (cardiomyocytes) stops at or shortly after birth and that the cardiomyocytes of an 80 year-old are the same ones he started out with.  The technology of radioactive carbon-dating … Continue reading →

It has been pointed out to me that this Blog and my Anti-Aging Firewalls treatise sites are now experiencing enough Internet traffic that I could generate revenue by accepting advertisements such as for proprietary dietary supplements, health cures, anti-aging treatments, … Continue reading →

Longevity research keeps showing up in unexpected places.  The US Army is pursuing research related to the third theory of aging in my Anti-Aging firewalls treatise, Mitochondrial Damage. They have an anti-aging research program called “Optimized Human Performance: Mitochondrial Energetics” … Continue reading →

Whatever else you may think about Henry Ford, I think you will agree he knew what he wanted and in large part got it.  I spent most of yesterday with cousins in Greenfield Village, a large historical theme park founded … Continue reading →

A number of proteins in the body play dual roles with respect to longevity – negative roles in some circumstances and good roles under other circumstances.  I mention three substances in this regard: VEGF, telomerase and P16(Ink4a). -         VEGF stands … Continue reading →

Pushing on 80 I am still quite young compared to my intended target age.  But I am already experiencing a major downside of longevity – and that is experiencing the sadness of death or debilitating illness of dear relatives and … Continue reading →

There seems to be no end to news stories about people 100 and over reporting their secrets to longevity.  Here is a sample from today’s news: :·        Being kind to people and eating healthy food (age 102) ·        Exercise (age … Continue reading →

What the heck does this mean?  It means an additional jigsaw-puzzle piece of knowledge relevant to the 14th theory of aging in my Anti-Aging Firewalls treatise, which is Decline in Adult Stem Cell Differentiation.  In this instance Sonic hedgehog (Shh) … Continue reading →

A large number of substances in the combined anti-aging firewalls dietary regimen such as green tea extract, ashwagandah, curcumin, resveratrol, olive leaf extract and boswellia seratta are herbal in origin and contain multiple phytochemicals that have pluripotent antiaging effects. Caffeic … Continue reading →