Monthly Archives: May 2009

Histone acetylase and deacetylase inhibitors

Readers, please don’t turn off on this post because the subject sounds too technical.  It relates to a major application area of epigenomics that has a lot to do with aging and anti-aging science. First, a simplified review of a … Continue reading

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Another rare genetic disease, and shortevity genes

Thanks again to Res for suggesting the lead which led to this post.  Adding to the list of rare genetic disorders affecting longevity recently discussed in this Blog, there is Wolfram Syndrome.  This is a disease long known to be … Continue reading

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Social ethics of longevity

Is increasing longevity be good for the society or does it pose a burden on younger people?  I outline where I am on this issue here because it has a lot to do with what motivates me to continue generating … Continue reading

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Hoyeraal-Hreidarsson Syndrome and telomere dysfunction

Exotic genetic diseases often provide important clues for the aging process, and I have previously discussed implications of Hutchinson-Gilford progeria and Werner Syndrome in this Blog.  This time, a research item on Hoyeraal-Hreidarsson Syndrome(HHS)  came to my attention.  “Hoyeraal-Hreidarsson syndrome … Continue reading

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State of autologous stem cell therapies

I searched the news this morning for items related to stem cell disease therapies.  I found over 60 items.  My impression is that the situation is a bit like commercial aviation was in 1926: everybody is talking about it, visionaries … Continue reading

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On the TRAIL of a selective cancer treatment

I have written previously on the difference between brute-force cancer therapies and highly focused new- generation ones in the pipeline.  See the post From four-pound hammer to smart molecules – on cancer treatments.  Radiation therapy and most forms of chemotherapy … Continue reading

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Anti-aging firewalls V2.0

The Anti-Aging Firewalls treatise is now a year old.  It is sometimes updated weekly, sometimes daily and has undergone several major revisions.  As expected when I first published the treatise, it is now very different from the original.  The latest … Continue reading

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Trojan-horse stem cells might offer an important new cancer therapy

There is a constant stream of news stories on new possible approaches to curing cancers.  Cancer research institutions love to see these.  They help to impress the funding sources.  But most of these press releases describe incremental progress on existing … Continue reading

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Consumer genomics

I discussed the general topic of individual DNA testing in an earlier post.  There is an important twist that I cover here.  Low-cost consumer-oriented genetic testing is making personal genomic information available to individuals in a way not intermediated by … Continue reading

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Anti-Aging Firewalls anniversary – and a thought

I published the first online version of the Anti-Aging Firewalls treatise a year ago and started this blog about six months ago.  A lot has happened on the longevity front during the period.  There have been 78 blog posts and … Continue reading

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