Comments on: Longevity genes, mTOR and lifespan http://www.anti-agingfirewalls.com/2009/05/15/longevity-genes-mtor-and-lifespan/ A weblog on the sciences and practices of living healthily very long - perhaps hundreds of years. Tue, 07 Feb 2012 16:23:41 +0000 hourly 1 http://wordpress.org/?v=3.2.1 By: The many faces of mTOR and rapamycin | AGING SCIENCES – Anti-Aging Firewalls http://www.anti-agingfirewalls.com/2009/05/15/longevity-genes-mtor-and-lifespan/#comment-56522 The many faces of mTOR and rapamycin | AGING SCIENCES – Anti-Aging Firewalls Mon, 13 Jun 2011 21:39:42 +0000 http://anti-agingfirewalls.com/2009/05/15/longevity-genes-mtor-and-lifespan/#comment-56522 [...] blog entries related to the mTOR pathways. For a general introduction I suggest readers review Longevity genes, mTOR and lifespan. Other relevant past blog entries include Viva mTOR! Caveat mTOR! and More mTOR links to aging [...] [...] blog entries related to the mTOR pathways. For a general introduction I suggest readers review Longevity genes, mTOR and lifespan. Other relevant past blog entries include Viva mTOR! Caveat mTOR! and More mTOR links to aging [...]

]]> By: peter http://www.anti-agingfirewalls.com/2009/05/15/longevity-genes-mtor-and-lifespan/#comment-21059 peter Sun, 08 Aug 2010 14:56:45 +0000 http://anti-agingfirewalls.com/2009/05/15/longevity-genes-mtor-and-lifespan/#comment-21059 Vince, I wonder if permanently inhibiting mTOR and activating autophagy is optimum. Reason being is that as we get older wound healing takes longer and it seems that we would want to periodically turn on the growth and healing mechanisms to a higher level, at least during periods when our tissues need repair (eg post-operation, sickness). I don't recall seeing this discussed anywhere and it seems that people in the know like yourself are opting for permanently suppressing mTOR and activating autophagy. I have no research to back up this speculation, but if memory serves there have been mice (or rat?) studies which showed that periodic, not permanent, CR, worked nearly as well as permanent CR. Just wondered if you have any thoughts along these lines.., Vince,

I wonder if permanently inhibiting mTOR and activating autophagy is optimum. Reason being is that as we get older wound healing takes longer and it seems that we would want to periodically turn on the growth and healing mechanisms to a higher level, at least during periods when our tissues need repair (eg post-operation, sickness). I don’t recall seeing this discussed anywhere and it seems that people in the know like yourself are opting for permanently suppressing mTOR and activating autophagy. I have no research to back up this speculation, but if memory serves there have been mice (or rat?) studies which showed that periodic, not permanent, CR, worked nearly as well as permanent CR. Just wondered if you have any thoughts along these lines..,

]]> By: admin http://www.anti-agingfirewalls.com/2009/05/15/longevity-genes-mtor-and-lifespan/#comment-4779 admin Sat, 07 Nov 2009 23:28:05 +0000 http://anti-agingfirewalls.com/2009/05/15/longevity-genes-mtor-and-lifespan/#comment-4779 Thanks Ginny. I will look your site over carefully. Vince Thanks Ginny. I will look your site over carefully.
Vince

]]> By: ginny http://www.anti-agingfirewalls.com/2009/05/15/longevity-genes-mtor-and-lifespan/#comment-4766 ginny Wed, 04 Nov 2009 08:18:28 +0000 http://anti-agingfirewalls.com/2009/05/15/longevity-genes-mtor-and-lifespan/#comment-4766 thanks for you provides this info.I found your site on Google and read a few of your other entires. Nice Stuff. I’m looking forward to reading more from you.suffer no more,if you like this knowledge www.longevity-club.com unraveling the health and longevity secret thanks for you provides this info.I found your site on Google and read a few of your other entires. Nice Stuff. I’m looking forward to reading more from you.suffer no more,if you like this knowledge http://www.longevity-club.com unraveling the health and longevity secret

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