Spices of life

Personally I love spicy foods, and ginger, curcumin and garlic have long been parts of my Anti-Aging Firewalls dietary supplement regimen.  There is an extensive body of literature supporting the health and potential anti-aging effects of spices.  Sage (salvia officinalis), thyme (thymus vulgaris), oregano (oreganol) and rosemary (rosmarinus officinalis) all have antioxidant properties(ref)(ref).  But the basic “reasoning for seasoning” appears to be inhibition of NF-kappaB(ref).  Control of expression of NF-kappaB is of course a major strategy for longevity proposed in the firewall for the Programmed Epigenomic Changes theory of aging.

To start off, hot chili peppers (capsaicin), ginger (gingerol) and turmeric (curcumin) are all inhibitors of NF-kappaB, and thereby regulate COX-2 and inflammation(ref)(ref)(ref)(ref).  The same general statements can be made for black pepper (piperine); it inhibits NF-kappaB expression, is an anti-inflammatory, etc.(ref).  The list goes on to include cloves, anise, cumin, fennel and garlic (ref).  Many of the active ingredients in these spices are also thought to be chemopreventative of cancers(ref) and have numerous other health benefits, curcumin being an example(ref).  “Curcumin, a yellow pigment present in the Indian spice turmeric (associated with curry powder), has been linked with suppression of inflammation; angiogenesis; tumorigenesis; diabetes; diseases of the cardiovascular, pulmonary, and neurological systems, of skin, and of liver; loss of bone and muscle; depression; chronic fatigue; and neuropathic pain(ref).”

So, in general I feel free to spice-up my foods as much as I want.  If you haven’t already read it, see the blog post Red wine, hot peppers and my uncle Gigi.

About Vincent Giuliano

Being a follower, connoisseur, and interpreter of longevity research is my latest career. I have been at this part-time for well over a decade, and in 2007 this became my mainline activity. In earlier reincarnations of my career. I was founding dean of a graduate school and a university professor at the State University of New York, a senior consultant working in a variety of fields at Arthur D. Little, Inc., Chief Scientist and C00 of Mirror Systems, a software company, and an international Internet consultant. I got off the ground with one of the earliest PhD's from Harvard in a field later to become known as computer science. In various ways I contributed to the Computer Revolution starting in the 1950s and the Internet Revolution starting in the late 1980s. I am now engaged in doing the same for The Longevity Revolution. I have published something like 200 books and papers as well as over 350 blog entries and have enjoyed various periods of notoriety. If you do a Google search on Vincent E. Giuliano, most if not all of the entries on the first few pages that come up will be ones relating to me. I have a general writings site at www.vincegiuliano.com and an extensive site of my art at www.giulianoart.com.
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3 Responses to Spices of life

  1. admin says:

    Nikos:
    No, frankly I have never considered that. There are hundreds of substances that inhibit NF-KappaB and I have not up to now taken particular notice of glutamine. Thank you for the suggestions and citations which I found interesting. I will look into the relative efficacy and safety of glutamine for NF-KappaB inhibition as well as the other effects of glutamine and possibly make that the subject of a new blog post.

  2. Spices of life.. May I repost it? :)

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