Comments on: Calorie restriction research roundup – Part II http://www.anti-agingfirewalls.com/2010/01/01/calorie-restriction-research-roundup-%e2%80%93-part-ii/ A weblog on the sciences and practices of living healthily very long - perhaps hundreds of years. Tue, 07 Feb 2012 16:23:41 +0000 hourly 1 http://wordpress.org/?v=3.2.1 By: admin http://www.anti-agingfirewalls.com/2010/01/01/calorie-restriction-research-roundup-%e2%80%93-part-ii/#comment-5541 admin Mon, 04 Jan 2010 02:49:31 +0000 http://anti-agingfirewalls.com/2010/01/01/calorie-restriction-research-roundup-%e2%80%93-part-ii/#comment-5541 Hi Marcus Most interesting comment. I am getting behind on keeping responsibly up with comments but I will read those items and get back with a comment on my reaction. Vince Hi Marcus

Most interesting comment. I am getting behind on keeping responsibly up with comments but I will read those items and get back with a comment on my reaction.

Vince

]]> By: Markus Look http://www.anti-agingfirewalls.com/2010/01/01/calorie-restriction-research-roundup-%e2%80%93-part-ii/#comment-5521 Markus Look Fri, 01 Jan 2010 14:02:31 +0000 http://anti-agingfirewalls.com/2010/01/01/calorie-restriction-research-roundup-%e2%80%93-part-ii/#comment-5521 Hello from Germany, Firstly, I want to thank you for publishing such outstandingly valuable information open source. I wanted to make a comment on the IGF-1 issue. Maybe the IGF1-BP3 should be taken into the equation and the question about administratin rGH as anti-aging strategy is IMHO also not yet closed to the disadvantage of rGH. The cross-sectional study below showed lower IGF-1, IGF1-BP3 in individuals displaying the metabolic syndrome who assumably are overweight.... PMID: 19415508.Cancer Causes Control. 2009 May 5. [Epub ahead of print] "RESULTS: Each of the components of metabolic syndrome (increased waist circumference, higher triglycerides, lower HDL cholesterol, higher blood pressure, higher fasting glucose and diabetes) was each associated with lower levels of IGF-I, IGF-BP3 and the Ratio IGF-I/IGF-BP3. Each of the metabolic syndrome components was also associated with higher levels of insulin. Participants with 3-5 components of metabolic syndrome had significantly lower IGF-I and higher IGF-BP3 levels compared to adults with 1-2 components or 0 components, after adjustment for potential confounders. Participants with diabetes had lower levels of IGF-I and IGF-BP3, and higher levels of insulin, regardless of the number of metabolic syndrome components...." I also recomment this article PMID: 19269702 best regards Markus Hello from Germany,

Firstly, I want to thank you for publishing such outstandingly valuable information open source.
I wanted to make a comment on the IGF-1 issue.

Maybe the IGF1-BP3 should be taken into the equation and the question about administratin rGH as anti-aging strategy is IMHO also not yet closed to the disadvantage of rGH.

The cross-sectional study below showed lower IGF-1, IGF1-BP3 in individuals displaying the metabolic syndrome who assumably are overweight….

PMID: 19415508.Cancer Causes Control. 2009 May 5. [Epub ahead of print]
“RESULTS: Each of the components of metabolic syndrome (increased waist circumference, higher triglycerides, lower HDL cholesterol, higher blood pressure, higher fasting glucose and diabetes) was each associated with lower levels of IGF-I, IGF-BP3 and the Ratio IGF-I/IGF-BP3. Each of the metabolic syndrome components was also associated with higher levels of insulin. Participants with 3-5 components of metabolic syndrome had significantly lower IGF-I and higher IGF-BP3 levels compared to adults with 1-2 components or 0 components, after adjustment for potential confounders. Participants with diabetes had lower levels of IGF-I and IGF-BP3, and higher levels of insulin, regardless of the number of metabolic syndrome components….”

I also recomment this article PMID: 19269702
best regards
Markus

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