Monthly Archives: October 2010

Telomere lengths, Part 3: Selected current research on telomere-related signaling

This blog entry reviews some recent research topics related to the molecular biology of telomere length homeostasis and to impacts of telomere lengths and cell maturation on health on aging. This is the third in a 3-part mini-series of blog … Continue reading

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Telomere lengths, Part 2: Lifestyle, dietary, and other factors associated with telomere shortening and lengthening

This blog entry provides an update on 2010 research relating to how certain everyday factors such as lifestyle, exercise and diet affect telomere lengths.  This is the second in a 3-part mini-series of blog posts concerned with the implications of … Continue reading

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Telomere lengths, Part 1: Telomere lengths, cancers and disease processes

Telomere lengths and the complex processes of telomere homeostasis are being researched intensively from a number of viewpoints.   However, it has been some time since I have discussed issues related to telomere lengths in this blog.  In this Part 1 … Continue reading

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Genomic stability, DNA repair and the sirtuin SIRT6

One theory of aging is that the genome and other DNA of an organism accumulate increasing numbers of errors with age and that these errors are responsible for the macroscopic phenomenon we call “aging.” See the second theory of aging … Continue reading

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Another guided-missile cancer therapy – that works

A small biotech company, ImmunoGen, has been developing targeted therapies for cancers, therapies based on attaching anticancer drug payloads to antibodies that home in on cancer cells.  This is another “guided missile” strategy that promises to increase the efficacy and … Continue reading

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A breakthrough in producing high-fidelity induced pluripotent stem cells

A newly-reported breakthrough in technology for generating high-fidelity induced pluripotent stem cells (iPSCs) suggests that these cells will soon be available and safe for use for in people.  The implications for regenerative medicine and extending human longevity may be profound.  … Continue reading

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Indefinite life extension – Dialog with Marios Kyriazis

Marios Kyriazis has invited me to engage with him in a dialog about the possibility of indefinite life extension and our first e-mail exchange is included here.  Dr. Kyriazis is a well-known physician and researcher in the field of anti-aging … Continue reading

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Gearing up for the war on aging

The stage for this blog entry was set by the recent one If we can multiply lifespans of nematodes by seven, why have we not been able to get anywhere with significant human lifespan extension?  The way things are going … Continue reading

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