The making of a dietary supplement – the long and short histories of it

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    By Vince Giuliano  June 3 2019 This blog entry tells the stories of how our new dietary supplement 4 Herb Synergy came into being.  As such, this blog entry tells two short histories: a universal history over more than … Continue reading

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INFLAMMATION PART 6: THE SCIENCE BEHIND THE 4 HERB SYNERGY DIETARY SUPPLEMENT

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Ancient plant wisdom meets nanotechnology By Vince Giuliano                                                                       May 28, 2019  This blog entry is concerned with a new dietary supplement that my colleagues I have sourced, called 4 Herb Synergy. It is concerned with the scientific considerations we have … Continue reading

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UPDATE ON LONGEVITY INTERVENTIONS – MAINLY PERSONAL

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“Start with the impossible. Proceed calmly towards the improbable. No worry, there are at least five exits.” —Father Daniel Berrigan By Vince Giuliano 4/11/19  This blog entry is about my ideas about my personal health and longevity. It is not … Continue reading

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AGING, CELL AND TISSUE REPAIR, RENEWAL AND REGENERATION, INFLAMMATION AND THE SASP

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By Vince Giuliano INTRODUCTION Many of us who have studied aging have long believed that, sooner or later we would discover keys to a long and healthy life via biological repair, renewal and regenerative processes. Based on what we have … Continue reading

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Inflammation Part 5: Inflammasomes – science of and disease implications

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By James P. Watson and Vince Giuliano Inflammasomes are multimeric self-assembling protein complexes within the cytosol of mammalian cells, pattern-recognizing components of the innate immune system.  They can be thought of as finely tuned alarm, triggering and amplifying systems that … Continue reading

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2018 meeting of the International Dose-Response Society

By Vince Giuliano As in previous years, I am posting this note regarding the forthcoming 2018 annual meeting of the International Dose-response Society.  It will be held as usual on the Campus of the University of Massachusetts in Amherst MA on April … Continue reading

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THE DOUBLE GENE KNOCKOUT BEHIND OUR OBESITY EPIDEMIC

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By James P Watson with assistance and added commentary by Vince Giuliano This is a story of how we got here to our obesity and metabolic disease epidemic.  Goes a bit back – around 30-40 million years – with another … Continue reading

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TALES OF NAD+ POWERPOINT PRESENTATION

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By Vince Giuliano Here is the PowerPoint presentation I made at the 3 rd Annual NAD Summit Conference on January 27 at 2 PM in San Diego. TALES OF NAD+  Just double click on the following link to download it. … Continue reading

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Part 2 of interventions that reduce all cause mortality (ACM) – Metformin

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by James P Watson and Vince Giuliano There is a community of self-experimenters who are taking the drug Metformin, not because they are diabetic or prediabetic, the FDA-approved reasons for prescribing the drug, but rather because they believe it probably … Continue reading

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Inflammation Part 4 – PCSK9 inhibition – Also Part 1 of interventions that reduce all cause mortality (ACM)

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By James P Watson with inputs and editorial assistance by Vince Giuliano I.  INTRODUCTION This is the fourth in what we expect will be an open-ended series of blog posts concerned with chronic inflammation.  Parts 1-6 are already published  It … Continue reading

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