Search Results for: Key roles of glia and microglia in age-related neurodegenerative diseases

Key roles of glia and microglia in age-related neurodegenerative diseases

Previously I have written about the roles of glia and microglia in Alzheimer’s disease and in spinal cord injury.  This blog entry reports on recent research which documents the importance of glial pathology as a general underlying factor in essentially … Continue reading

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Inflammation Part 7: Neurohormesis, neuroinflammatory diseases, and their treatment by mushroom substances (Section 1)

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Can a mushroom play an important role in the health and anti-aging picture?  Recent research says Yes, and this blog entry tells the story Current medical treatments for age-related neurological brain diseases like Alzheimer’s and Parkinson’s remain largely ineffective, despite … Continue reading

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Inflammation Part 3: resolving inflammation – resolvins, protectins, maresins and lipoxins

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By Vince Giuliano This Part 3 of the Inflammation series of blog entries is concerned with the all-important resolution phase of inflammation, how acute inflammation goes away under ideal conditions instead of hunkering down to lingering and dangerous chronic inflammation. … Continue reading

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A simple, comprehensive plan to prevent or reverse Alzheimer’s Disease and other neurodegenerative diseases – Part 1: The Plan

By James P Watson, with contributions and editorial assistance by Vince Giuliano  INTRODUCTION AND OVERALL PRINCIPLES This is the first of a pair of blog entries concerned with dementias – neurological diseases including Alzheimer’s Disease (AD) and its cousins.  This … Continue reading

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The Amyloid Beta face of Alzheimer’s Disease

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By Jim Watson with editorial and minor contributions by Vince Giuliano Much has been learned over the years about Alzheimer’s Disease (AD) and there are several sides to the unfolding story which considered together are making more and more sense.  … Continue reading

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Dietary factors and dementia – Part 1: important recent research

By Vince Giuliano This is the first of three blog entries focusing on research during the last two years relating diet, dietary substances and supplements to late-onset dementias including Alzheimer’s disease (AD), and to the potential roles of such substances … Continue reading

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AGING, CELL AND TISSUE REPAIR, RENEWAL AND REGENERATION, INFLAMMATION AND THE SASP

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By Vince Giuliano INTRODUCTION Many of us who have studied aging have long believed that, sooner or later we would discover keys to a long and healthy life via biological repair, renewal and regenerative processes. Based on what we have … Continue reading

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Inflammation Part 5: Inflammasomes – science of and disease implications

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By James P. Watson and Vince Giuliano Inflammasomes are multimeric self-assembling protein complexes within the cytosol of mammalian cells, pattern-recognizing components of the innate immune system.  They can be thought of as finely tuned alarm, triggering and amplifying systems that … Continue reading

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The Alpha and Beta of GSK-3s – first in the Strange but Powerful Molecules Series

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The Molecules that Play Dr. Jeckel and Mr. Hyde in Aging, Alzheimer’s Disease, and Type II Diabetes By James P Watson, with summary and contributions from Vince Giuliano Introduction – GSK-3s – The “Dr. Jeckel and Mr. Hyde” Molecules Have … Continue reading

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The Master Regulator of Aging? – Redox, Glutatione and Cysteine, Part 1

By Dan Campagnoli (Welcome Dan, as a researcher and writer for this blog.  Jim Watson and I agree that with what is laid out in this blog entry, you clearly win both of the prizes in our contest Aging science … Continue reading

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