Search Results for: telomerase

Part 4 of the NAD world: the NQ01 gene, the Warburg effect, SIRT 1 and inflammation, and possible interventions

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By James P Watson with contributions and editorial assistance by Vince Giuliano This Part 4 blog entry goes even further into the extended NAD story, examining important subtopics: The ratio NAD+/NADH in cells and the body, which may be as … Continue reading

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30 Major Factors that Control SIRT1 Expression, SIRT1 Activity, and SIRT1-mediated Aging. Part 3 of the series NAD+ an emerging framework for health and life extension

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  By James P Watson with comments and editorial assistance by Vince Giuliano Introduction by Vince Giuliano: This is the third blog entry in the series NAD+ an emerging framework for health and life extension.  The first two entries were  … Continue reading

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A simple, comprehensive plan to prevent or reverse Alzheimer’s Disease and other neurodegenerative diseases – Part 1: The Plan

By James P Watson, with contributions and editorial assistance by Vince Giuliano  INTRODUCTION AND OVERALL PRINCIPLES This is the first of a pair of blog entries concerned with dementias – neurological diseases including Alzheimer’s Disease (AD) and its cousins.  This … Continue reading

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NAD+ an emerging framework for life health and life extension — Part 2: Deeper into the NAD World, hopeful interventions

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By James P Watson with contributions and assistance by Vince Giuliano This is Part 2 of what will likely be a six-part series of blog entries related to the metabolic cofactor NAD+ and what goes on in the NAD World,  … Continue reading

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NAD+ an emerging framework for health and life extension — Part 1: The NAD World

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By Vince Giuliano with inputs from  James P. Watson Accelerated by the publication in December 2013 of a seminal paper by David Sinclair and his US and Australian colleagues(ref), there has been increasing interest and excitement about the prospects of … Continue reading

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The Alpha and Beta of GSK-3s – first in the Strange but Powerful Molecules Series

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The Molecules that Play Dr. Jeckel and Mr. Hyde in Aging, Alzheimer’s Disease, and Type II Diabetes By James P Watson, with summary and contributions from Vince Giuliano Introduction – GSK-3s – The “Dr. Jeckel and Mr. Hyde” Molecules Have … Continue reading

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FIVE-YEAR PROGRESS REPORT ON MAJOR TRENDS IMPACTING ON LONGEVITY.

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By Vince Giuliano This is a progress report on the changing state of human longevity during the five-year lifespan of this blog.  It reviews major trends and forces impacting on our lifespans, both scientific and social.  Longevity can be viewed … Continue reading

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Nuclear Aging: The View from the Telomere end of the Chromosome – Part 3 – Telomere Molecular Biology and GUT implications – The two faces of P53

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By James P Watson with editorial assistance and comments by Vince Giuliano This is Part 3 of 3 in the series The View from the Telomere end of the Chromsome.  Because of the length of the telomere story, we divided … Continue reading

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Nuclear Aging: The View from the Telomere end of the Chromosome – Part 2 – Telomere Molecular Biology

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By James P Watson with editorial assistance and a few comments by Vince Giuliano This is Part 2 of 3 in the series The View from the Telomere end of the Chromsome.  Because of the length of the extended telomere story, we … Continue reading

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Nuclear Aging: The View from the Telomere end of the Chromosome Part 1 – context, history, and about telomere lengths

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By James P Watson with Preface and editorial assistance by Vince Giuliano Preface by Vince Giuliano According to the latest theories of cosmology, the universe has no center.  However, anyplace in the universe, including where we are on Earth, can … Continue reading

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