Category Archives: Uncategorized

Breakthrough telomere research finding

Maria Blasco heads the Telomeres & Telomerase Group at the Spanish National Cancer Center in Madrid.  She and her group have produced a number of important papers over recent years contributing to our understanding of telomere/telomerase science. A November 2009 … Continue reading

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Hormesis and age retardation

An important approach to retarding aging that I have not discussed explicitly so far is hormesis, challenging cells and body systems by mild stress resulting in them becoming stronger and resistant to aging(ref).  The stress can be physical, chemical and … Continue reading

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A gene therapy home run

The home run reported this week was in a practice game in a minor league.  But nonetheless the results are impressive and lead to hope for those suffering from certain forms of congenital blindness and vision impairment.  The report leading … Continue reading

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Senesco and the Factor 5A1 gene

Senesco is a small research-based company specializing in “genetic technologies designed to regulate cell death.”  A company that started out with focus on commercial agriculture, it has been exploring a proprietary gene, Factor 5A1, that might well also have a … Continue reading

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Longevity gods and goddesses – old and new

If you want to live a very long life and are tired of the highly technical stuff in this blog, you might want to appeal to one of the traditional longevity gods or goddesses.  Some of these gods and goddesses, … Continue reading

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ALD and lentivirus vectors for gene therapy

Gene therapy – the substituting of inherited defective genes with good ones – does not have an outstanding success record but now is getting off the ground.  As pointed out in an editorial in the Nov 6 2009 issue of … Continue reading

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Vitamin D – don’t fall for it

Falling is one of the major causes of debilitation and accelerated death among the elderly.  Older as well as recent research indicates that old folks in and out of nursing homes who take regular Vitamin D supplements fall a lot … Continue reading

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Spinal cord injury pain – a personal story and a new paradigm

Chronic nagging back pain can result from spinal cord injury (SCI) and can lead to pain in other parts of the body that are in fact not injured.  It can be very difficult to diagnose and a person suffering from … Continue reading

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DNA demethylation – a new way of coming at cancers

I got into this topic indirectly, starting out by researching what is known about DNA demethylation in response to a comment by Res on my blog post Homicide by DNA methylation.  I found a great deal of interesting material related … Continue reading

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Revisiting the naked mole rat – two factors we can emulate for longevity

The lowly naked mole rat is in the news again.  I talked about the little critter in my in my February 2009 post Animal models of aging – the African naked mole rat.  I said “This little critter is the … Continue reading

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