Search Results for: telomerase

Revisiting the naked mole rat – two factors we can emulate for longevity

The lowly naked mole rat is in the news again.  I talked about the little critter in my in my February 2009 post Animal models of aging – the African naked mole rat.  I said “This little critter is the … Continue reading

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Pythons, cell senescence and telomere torments

An interesting report came to my attention relating to telomeres in pythons, and this set me off for the umpteenth time pursuing further research and thoughts about cell senescence, telomere lengths and telomerase. I share that all here. First of … Continue reading

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The human liver – a model for organ regeneration?

This post reviews some key research findings regarding liver regeneration and discusses what is known about the mechanisms involved.   It turns out that a bunch of my favorite blog topics are involved: telomerase, stem/progenitor cells, mTOR signaling, MAPK signaling, NOTCH … Continue reading

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Revisiting telomere shortening yet-again

After coming up from burying myself for a month in the research leading to the Stem Cell Supply Chain Breakdown theory of aging, I decided to check on recent research relating this theory to the Telomere Shortening and Damage theory … Continue reading

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Cordyceps militaris and cancer

“Cordyceps militaris is pretty much the coolest mushroom ever(ref).”  It is a caterpillar killer that gets inside a pupa or larva (usually of a butterfly or moth).  From there it grows inside and bursts outside the insect shell in a horror … Continue reading

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Immunosenescence – No thanks for the memories

If extremely long lives are going to become possible, it will be necessary to discover effective means for averting or delaying immunosenescence, the process of the immune system losing functionality with advanced aging. This is a mini-treatise on immunosenescence.  It … Continue reading

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An emerging new view of aging – the stem cell supply chain

This is a long and important blog entry, going to the heart of “What is aging and what can be done about it?” Stem cell research, churning along at a ferocious rate, is revealing a new view of aging from … Continue reading

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Hair stem cells

Some readers of this blog have expressed interest in my new hair growth which I have tentatively attributed to telomerase activation resulting from taking an astragaloside IV supplement.  This has led me to look into what recent research tells us about hair … Continue reading

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Now hear this

Joe’s Wife:  Jerry just called from Brown’s Boat Basin.  Old Joe:  Who fell down?  Did you say Larry or Mary? And what’s that about a brown raisin in your throat? Joe’s Wife:  “YOUR SON JERRY PHONED.  Said he wants to … Continue reading

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On cancer stem cells

A relatively new approach to looking at and treating cancers is to focus on cancer stem cells, a small subpopulation of cancer cells in a tumor that are capable or reproducing indefinitely and differentiating into mature cancer cells.  “Cancer stem … Continue reading

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