Author Archives: Vince Giuliano

About Vince Giuliano

Being a follower, connoisseur, and interpreter of longevity research is my latest career, since 2007. I believe I am unique among the researchers and writers in the aging sciences community in one critical respect. That is, I personally practice the anti-aging interventions that I preach and that has kept me healthy, young, active and highly involved at my age, now 96. I am as productive as I was at age 45. I don’t know of anybody else active in that community in my age bracket. In particular, I have focused on the importance of controlling chronic inflammation for healthy aging, and have written a number of articles on that subject in this blog. In 2014, I created a dietary supplement to further this objective. In 2019, two family colleagues and I started up Synergy Bioherbals, a dietary supplement company that is now selling this product. As of November 2025, I believe the longevity interventions I have already published in this blog and are being followed by me will easily get me to age 100 and somewhat beyond, still healthy, highly functional and working Further, I have been researching and will be pubishing about additional interventions which I expect will buy me several additional years of active healthy living. In earlier reincarnations of my career. I was Founding Dean of a graduate school and a full University Professor at the State University of New York, a senior consultant working in a variety of fields at Arthur D. Little, Inc., Chief Scientist and C00 of Mirror Systems, a software company, and an international Internet consultant. I got off the ground with one of the earliest PhD's from Harvard in a field later to become known as computer science. Because there was no academic field of computer science at the time, to get through I had to qualify myself in hard sciences, so my studies focused heavily on quantum physics. In various ways I contributed to the Computer Revolution starting in the 1950s and the Internet Revolution starting in the late 1980s. I am now engaged in doing the same for The Longevity Revolution. I have published something like 200 books and papers as well as over 430 substantive.entries in this blog, and have enjoyed various periods of notoriety. If you do a Google search on Vincent E. Giuliano, most if not all of the entries on the first few pages that come up will be ones relating to me. I have a general writings site at www.vincegiuliano.com and an extensive site of my art at www.giulianoart.com. Please note that I have recently changed my mailbox to vegiuliano@agingsciences.com.

CAR adoptive stem cell immunotherapy– an emerging new weapon against cancers and other incurable diseases

By Vince Giuliano There is current excitement about a new approach to using a person’s own immune system to fight and defeat otherwise incurable cancers: Adoptive immunotherapy, a technology that is currently the subject of multiple clinical trials.  Here, I … Continue reading

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Latest p16(Ink4a) senescence-reversing research – an important but not game-changing contribution

By Vince Giuliano The press has recently picked up heavily on work by Mayo Clinic researchers related to reversal of cell-senescence in-vivo via inhibition of expression of the protein p16(Ink4a).  The research has been heralded by such headlines as Cell … Continue reading

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Key roles of glia and microglia in age-related neurodegenerative diseases

Previously I have written about the roles of glia and microglia in Alzheimer’s disease and in spinal cord injury.  This blog entry reports on recent research which documents the importance of glial pathology as a general underlying factor in essentially … Continue reading

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In-vivo cell reprogramming for longer lives

This blog entry unifies three themes that have repeatedly been expressed in this blog: 1.  The possibility of extending lives via using “rebooted” cells, that is induced pluripotent stem cells (iPSCs), 2.  the key role of epigenetic factors in determining … Continue reading

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Progress update on induced pluripotent stem cells

By Vince Giuliano The last few months have seen the continuation of an extraordinary pace of research related to induced pluripotent stem cells (iPSCs), a technology stream that has been widely heralded as key for organ regeneration, for regenerative medicine, … Continue reading

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Phytosubstances – focus on cat’s claw

There is a substantial amount current research on cat’s claw (uncaria tomentosa, in Spanish Uña de Gato), a herb imported from the Peruvian Amazon.  This blog entry documents some of the properties of this remarkable substance and a number of … Continue reading

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Editorial – A shift in a key aging sciences paradigm

By Vince Giuliano Mainline scientific theories may have long lifespans but are inevitably overturned as accumulating evidence renders them obsolete and brings alternative theories to the fore.  We saw this in physics over 100 years ago when relativity theory and … Continue reading

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Aging and the immune system – focus on naïve T-cells

By Vince Giuliano The human immune system provides our defenses against pathogens. This blog entry focuses on research on T-cells. a family of cells in the immune system.  The research is relevant to aging because it challenges the traditional view … Continue reading

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Focus on bitter melon

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Bitter melon has antiviral, antimalerial, cardioprotective, and neuroprotective properties.  Bitter melon is potentially an important dietary tool for combating insulin resistance, diabetes and obesity.  This blog entry reviews the relevant research. Bitter melon (BM) is one of those strange-looking fruits … Continue reading

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Age-related cognitive decline: focus on interventions

In previous blog entries and in my longevity treatise, I have discussed factors involved in age-related decline in memory and cognitive functioning.  This blog entry is concerned with research findings that suggest practical approaches to slowing or possibly reversing such … Continue reading

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