Author Archives: Vince Giuliano

About Vince Giuliano

Being a follower, connoisseur, and interpreter of longevity research is my latest career, since 2007. I believe I am unique among the researchers and writers in the aging sciences community in one critical respect. That is, I personally practice the anti-aging interventions that I preach and that has kept me healthy, young, active and highly involved at my age, now 93. I am as productive as I was at age 45. I don’t know of anybody else active in that community in my age bracket. In particular, I have focused on the importance of controlling chronic inflammation for healthy aging, and have written a number of articles on that subject in this blog. In 2014, I created a dietary supplement to further this objective. In 2019, two family colleagues and I started up Synergy Bioherbals, a dietary supplement company that is now selling this product. In earlier reincarnations of my career. I was Founding Dean of a graduate school and a full University Professor at the State University of New York, a senior consultant working in a variety of fields at Arthur D. Little, Inc., Chief Scientist and C00 of Mirror Systems, a software company, and an international Internet consultant. I got off the ground with one of the earliest PhD's from Harvard in a field later to become known as computer science. Because there was no academic field of computer science at the time, to get through I had to qualify myself in hard sciences, so my studies focused heavily on quantum physics. In various ways I contributed to the Computer Revolution starting in the 1950s and the Internet Revolution starting in the late 1980s. I am now engaged in doing the same for The Longevity Revolution. I have published something like 200 books and papers as well as over 430 substantive.entries in this blog, and have enjoyed various periods of notoriety. If you do a Google search on Vincent E. Giuliano, most if not all of the entries on the first few pages that come up will be ones relating to me. I have a general writings site at www.vincegiuliano.com and an extensive site of my art at www.giulianoart.com. Please note that I have recently changed my mailbox to vegiuliano@agingsciences.com.

If we can multiply lifespans of nematodes by seven, why have we not been able to get anywhere with significant human lifespan extension?

Posted on 29. September 2010 by Vince Giuliano

Back in a July 2009 blog post Life extension by a factor of 10, I described how radical life extension has been achieved in baker’s yeast.  The most-recent blog entry posted two days ago New extraordinary longevity lessons from the … Continue reading →

Posted in Uncategorized | 7 Comments

New extraordinary longevity lessons from the nematode

Posted on 26. September 2010 by Vince Giuliano

Genetic lifespan regulation has been studied extensively in the nematode roundworm Caenorhabditis elegans (C-elegans) since the 1980s.  Hundreds of research papers have been written on this topic.  And I have generated a number of blog entries on longevity pathways known … Continue reading →

Posted in Uncategorized | 7 Comments

Klotho, phosphates, cola drinks and longevity

Posted on 21. September 2010 by Vince Giuliano

The October 2009 blog entry Klotho anti-aging gene in the news describes how the Klotho protein exhibits anti-aging effects in mice when over-expressed and accelerates aging when under-expressed, Klotho’s role with respect to the vitamin D receptor (VDR),  and how … Continue reading →

Posted in Uncategorized | 9 Comments

Smurf2 in senescence, aging and diseases

Posted on 16. September 2010 by Vince Giuliano

Smurf2 is a fascinating gene and enzyme that plays a number of key roles throughout life in people, ranging from roles in embryonic development and stem cell differentiation to ones relating to cell senescence and accelerated (or delayed) aging.  It … Continue reading →

Posted in Uncategorized | 2 Comments

HSP70 to the rescue – But, no, no! That’s not what we want for cancer cells

Posted on 12. September 2010 by Vince Giuliano

The July 2010 blog entry HSP70 to the rescue describes how heat shock protein 70 (HSP70) works to promote survival of cells under stress and provides examples of the positive hormetic effects of this chaperone protein.  For example HSP70 is … Continue reading →

Posted in Uncategorized | Leave a comment

Valproic acid – The phoenix drug arises again

Posted on 7. September 2010 by Vince Giuliano

The chemical valproic acid has been around for a very long time.  It was first synthesized in 1882 and for a great many years it seemed to be not very useful. However, over its 128 year history valproic acid has … Continue reading →

Posted in Uncategorized | 14 Comments

Antagonistic pleiotropy revisited – for the last time

Posted on 2. September 2010 by Vince Giuliano

Most times when I meet old friends who I have not seen for a long time, the old magic comes back.  There is new vitality in our new context of relationship.  With certain other people met again after many years, … Continue reading →

Posted in Uncategorized | 4 Comments

Curcumin, cancer and longevity

Posted on 27. August 2010 by Vince Giuliano

This blog entry is a companion and sequel to the previous one Neurogenesis, curcumin and longevity.  I focus here on the extensive research related to the anti-cancer properties of curcumin and go further into an issue raised in the last … Continue reading →

Posted in Uncategorized | 17 Comments

Neurogenesis, curcumin and longevity

Posted on 24. August 2010 by Vince Giuliano

I have discussed both neurogenesis and curcumin in my treatise and in numerous blog entries but have never examined their relationship.  This blog entry is about the actions of curcumin in promoting neurogenesis in the hippocampus and highly-likely mental-health implications … Continue reading →

Posted in Uncategorized | 9 Comments

PGC-1-alpha and exercise

Posted on 18. August 2010 by Vince Giuliano

You can probably expect to hear a lot about PGC-1-alpha as time goes on because this remarkable substance is turning out to have a lot to do with health and longevity.  It appears to be the mediator of the health … Continue reading →

Posted in Uncategorized | 8 Comments