Author Archives: Vince Giuliano

About Vince Giuliano

Being a follower, connoisseur, and interpreter of longevity research is my latest career, since 2007. I believe I am unique among the researchers and writers in the aging sciences community in one critical respect. That is, I personally practice the anti-aging interventions that I preach and that has kept me healthy, young, active and highly involved at my age, now 93. I am as productive as I was at age 45. I don’t know of anybody else active in that community in my age bracket. In particular, I have focused on the importance of controlling chronic inflammation for healthy aging, and have written a number of articles on that subject in this blog. In 2014, I created a dietary supplement to further this objective. In 2019, two family colleagues and I started up Synergy Bioherbals, a dietary supplement company that is now selling this product. In earlier reincarnations of my career. I was Founding Dean of a graduate school and a full University Professor at the State University of New York, a senior consultant working in a variety of fields at Arthur D. Little, Inc., Chief Scientist and C00 of Mirror Systems, a software company, and an international Internet consultant. I got off the ground with one of the earliest PhD's from Harvard in a field later to become known as computer science. Because there was no academic field of computer science at the time, to get through I had to qualify myself in hard sciences, so my studies focused heavily on quantum physics. In various ways I contributed to the Computer Revolution starting in the 1950s and the Internet Revolution starting in the late 1980s. I am now engaged in doing the same for The Longevity Revolution. I have published something like 200 books and papers as well as over 430 substantive.entries in this blog, and have enjoyed various periods of notoriety. If you do a Google search on Vincent E. Giuliano, most if not all of the entries on the first few pages that come up will be ones relating to me. I have a general writings site at www.vincegiuliano.com and an extensive site of my art at www.giulianoart.com. Please note that I have recently changed my mailbox to vegiuliano@agingsciences.com.

AMPK and longevity

The AMPK signaling pathway is one that is increasingly being viewed as playing a central role in metabolism and growth(ref). And that pathway appears to have a lot to do with longevity.  In fact, it is possible that some degree … Continue reading

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Stress, exercise and telomere lengths

I have frequently asserted that telomere lengths do not decline in a uniform manner through life but depend on the interaction of multiple endogenous and extrinsic factors.  Two important factors are stress and exercise.  A new study in Plos One … Continue reading

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Humanin, health and aging

Ever hear of humanin?  At the Paul K Glenn Symposium on Aging yesterday at Harvard, Dr. Pinchas Cohen gave a talk on The New World of Mitochondrial Proteins featuring humanin and other closely related proteins.  The subject is important because … Continue reading

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The free radical theory of aging. Is it really a theory of aging?

The free radical theory of aging, also known as the Oxidative Damagetheory of aging is over 50 years old and is perhaps the most-studied and most venerable of all the theories of aging.   But at least one line of … Continue reading

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Ghrelin hunger, obesity and aging

Have you heard about Ghrelin?  No, I am not talking about a new grill cleaner or a men’s girl-attracting perfume or a new shortstop for the Yankees.  Ghrelin is a hormone deeply involved in a very important current health condition, … Continue reading

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Back to blueberries

I wrote about blueberries back in September 2009 in the blog entry Blueberries and health – the research case, citing 11 research citations there on their positive health effects.  I have long been in the habit of eating a cupful … Continue reading

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Calorie restriction mimetics – focus on avocado extract

I have written about calorie restriction (CR) a number of times in this blog. CR is the most-proven approach to life extension, involving an ancient biological pathway that works across a variety of species. This blog entry focuses on CR … Continue reading

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Is acetaminophen an anti-aging drug? Probably not.

Virtually everybody has taken acetaminophen (also known as paracetamol) from time to time; probably a lot of it over the years.  It is of course the key ingredient in the over-the-counter pain-killer Tylenol®,  is widely sold as an inexpensive over-the-counter … Continue reading

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A near-term application for iPSCs – making cell lines for drug testing

I have written a number of times in this blog about iPSCs (induced pluripotent stem cells) including the exciting possibility of closing the loop in the stem cell supply chain and thereby enabling very long lives.  See the posts IPSCs, … Continue reading

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Epigenetics, inflammation, cancer, immune system, neurological and cardiovascular disease and aging

In my presentation Towards a Systems Theory of Aging I argue that the two theories Programmed epigenomic changes and Decline in functioning of the stem cell supply chain are complimentary and equivalent and have the potential for providing a framework … Continue reading

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