Search Results for: telomerase

Telomere lengths and the complex processes of telomere homeostasis are being researched intensively from a number of viewpoints.   However, it has been some time since I have discussed issues related to telomere lengths in this blog.  In this Part 1 … Continue reading →

The stage for this blog entry was set by the recent one If we can multiply lifespans of nematodes by seven, why have we not been able to get anywhere with significant human lifespan extension?  The way things are going … Continue reading →

Back in a July 2009 blog post Life extension by a factor of 10, I described how radical life extension has been achieved in baker’s yeast.  The most-recent blog entry posted two days ago New extraordinary longevity lessons from the … Continue reading →

Smurf2 is a fascinating gene and enzyme that plays a number of key roles throughout life in people, ranging from roles in embryonic development and stem cell differentiation to ones relating to cell senescence and accelerated (or delayed) aging.  It … Continue reading →

You can probably expect to hear a lot about PGC-1-alpha as time goes on because this remarkable substance is turning out to have a lot to do with health and longevity.  It appears to be the mediator of the health … Continue reading →

Recent publications have surfaced substances that may contribute to aging including favorites used to extend longevity.  Also, it has cast light on longevity due to calorie restriction suggesting that what counts is not the calories as much as the food … Continue reading →

Longevity science had been a hobby for me for a long time and about 3 years ago I decided to pursue it as a new full-time career.  I put the first version of my treatise Anti-Aging Firewalls – The Science … Continue reading →

I have frequently asserted that telomere lengths do not decline in a uniform manner through life but depend on the interaction of multiple endogenous and extrinsic factors.  Two important factors are stress and exercise.  A new study in Plos One … Continue reading →

I have written a number of times in this blog about iPSCs (induced pluripotent stem cells) including the exciting possibility of closing the loop in the stem cell supply chain and thereby enabling very long lives.  See the posts IPSCs, … Continue reading →

Melanoma is the most serious form of skin cancer. It is a cancer “–  of melanocytes which are found predominantly in skin but also in the bowel and the eye (see uveal melanoma).  — Melanocytes are normally present in skin, … Continue reading →