Author Archives: Vince Giuliano

About Vince Giuliano

Being a follower, connoisseur, and interpreter of longevity research is my latest career, since 2007. I believe I am unique among the researchers and writers in the aging sciences community in one critical respect. That is, I personally practice the anti-aging interventions that I preach and that has kept me healthy, young, active and highly involved at my age, now 96. I am as productive as I was at age 45. I don’t know of anybody else active in that community in my age bracket. In particular, I have focused on the importance of controlling chronic inflammation for healthy aging, and have written a number of articles on that subject in this blog. In 2014, I created a dietary supplement to further this objective. In 2019, two family colleagues and I started up Synergy Bioherbals, a dietary supplement company that is now selling this product. As of November 2025, I believe the longevity interventions I have already published in this blog and are being followed by me will easily get me to age 100 and somewhat beyond, still healthy, highly functional and working Further, I have been researching and will be pubishing about additional interventions which I expect will buy me several additional years of active healthy living. In earlier reincarnations of my career. I was Founding Dean of a graduate school and a full University Professor at the State University of New York, a senior consultant working in a variety of fields at Arthur D. Little, Inc., Chief Scientist and C00 of Mirror Systems, a software company, and an international Internet consultant. I got off the ground with one of the earliest PhD's from Harvard in a field later to become known as computer science. Because there was no academic field of computer science at the time, to get through I had to qualify myself in hard sciences, so my studies focused heavily on quantum physics. In various ways I contributed to the Computer Revolution starting in the 1950s and the Internet Revolution starting in the late 1980s. I am now engaged in doing the same for The Longevity Revolution. I have published something like 200 books and papers as well as over 430 substantive.entries in this blog, and have enjoyed various periods of notoriety. If you do a Google search on Vincent E. Giuliano, most if not all of the entries on the first few pages that come up will be ones relating to me. I have a general writings site at www.vincegiuliano.com and an extensive site of my art at www.giulianoart.com. Please note that I have recently changed my mailbox to vegiuliano@agingsciences.com.

Neurogenesis, curcumin and longevity

I have discussed both neurogenesis and curcumin in my treatise and in numerous blog entries but have never examined their relationship.  This blog entry is about the actions of curcumin in promoting neurogenesis in the hippocampus and highly-likely mental-health implications … Continue reading

Posted in Uncategorized | 9 Comments

PGC-1-alpha and exercise

You can probably expect to hear a lot about PGC-1-alpha as time goes on because this remarkable substance is turning out to have a lot to do with health and longevity.  It appears to be the mediator of the health … Continue reading

Posted in Uncategorized | 8 Comments

Blog entries in the works

I have covered much of the “low hanging fruit” of the longevity sciences in the 304 existing blog entries written over the last two years.  Yet, developing a comprehensive understanding of the key aspects of aging requires harvesting fruit from … Continue reading

Posted in Uncategorized | 4 Comments

Skin Cancer immunotherapies

Immunotherapies are ones that mobilize the body’s own immune system defense against disease processes.  This blog entry is about immunotherapies for skin cancers, focusing on an effective older one known as imiquimod or by its trade name aldara, and a … Continue reading

Posted in Uncategorized | 20 Comments

Contrarian research findings: newly-identified aging villain substances; calorie restriction longevity is not due to calorie restriction

Recent publications have surfaced substances that may contribute to aging including favorites used to extend longevity.  Also, it has cast light on longevity due to calorie restriction suggesting that what counts is not the calories as much as the food … Continue reading

Posted in Uncategorized | 12 Comments

Turning P53 on in cancer cells

The P53 protein provides a first line of defense against cancers, causing cancer cells to commit apoptosis.  “p53 (also known as protein 53 or tumor protein 53), is a tumor suppressor protein that in humans is encoded by the TP53 … Continue reading

Posted in Uncategorized | 3 Comments

Diabetes Part 2: Lifestyle, dietary and supplement interventions

In the post Diabetes Part I: Biology and molecular dynamics of diabetes, I described a pathological biomolecular process through which diabetes arises from obesity or metabolic syndrome.  I also provided reference links to publications amplifying on the details of the … Continue reading

Posted in Uncategorized | 7 Comments

Diabetes Part I: Biology and molecular dynamics of diabetes

This is the first of two related blog posts on diabetes.  Here I review the nature of diabetes, and a commonly occurring biomolecular processes underlying the development of Type 2 diabetes.  I quote from several recent research papers relating diabetes … Continue reading

Posted in Uncategorized | 5 Comments

Alzheimer’s disease studies validate anti-aging firewalls suggestions

At the still-ongoing (as of July 12, 2010) meeting of the American Alzheimer’s Association in Honolulu, four different papers were presented that  validate components of the anti-aging firewalls regimen suggested in my treatise Anti-Aging Firewalls – The Science and Technology … Continue reading

Posted in Uncategorized | 9 Comments

Induced pluripotent stem cells – developments on the road to big-time utilization

I have written about developments relating to cell reprogramming and induced pluripotent stem cells (iPSCs) in several previous blog posts, the most recent including A near-term application for iPSCs – making cell lines for drug testing, Induced pluripotent stem cells … Continue reading

Posted in Uncategorized | 2 Comments