Author Archives: Vince Giuliano

About Vince Giuliano

Being a follower, connoisseur, and interpreter of longevity research is my latest career, since 2007. I believe I am unique among the researchers and writers in the aging sciences community in one critical respect. That is, I personally practice the anti-aging interventions that I preach and that has kept me healthy, young, active and highly involved at my age, now 93. I am as productive as I was at age 45. I don’t know of anybody else active in that community in my age bracket. In particular, I have focused on the importance of controlling chronic inflammation for healthy aging, and have written a number of articles on that subject in this blog. In 2014, I created a dietary supplement to further this objective. In 2019, two family colleagues and I started up Synergy Bioherbals, a dietary supplement company that is now selling this product. In earlier reincarnations of my career. I was Founding Dean of a graduate school and a full University Professor at the State University of New York, a senior consultant working in a variety of fields at Arthur D. Little, Inc., Chief Scientist and C00 of Mirror Systems, a software company, and an international Internet consultant. I got off the ground with one of the earliest PhD's from Harvard in a field later to become known as computer science. Because there was no academic field of computer science at the time, to get through I had to qualify myself in hard sciences, so my studies focused heavily on quantum physics. In various ways I contributed to the Computer Revolution starting in the 1950s and the Internet Revolution starting in the late 1980s. I am now engaged in doing the same for The Longevity Revolution. I have published something like 200 books and papers as well as over 430 substantive.entries in this blog, and have enjoyed various periods of notoriety. If you do a Google search on Vincent E. Giuliano, most if not all of the entries on the first few pages that come up will be ones relating to me. I have a general writings site at www.vincegiuliano.com and an extensive site of my art at www.giulianoart.com. Please note that I have recently changed my mailbox to vegiuliano@agingsciences.com.

Niacin or niacinamide supplementation – good or bad idea?

Posted on 30. March 2010 by Vince Giuliano

It was disturbing to some readers when I characterized niacinamide as a pro-aging substance in the March 24 blog post  SIRT1, mTOR, NF-kappaB and resveratrol, as it was disturbing to me when I first came to that realization years ago.  … Continue reading →

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SIRT1, the hypoxic response, autophagy and hormesis

Posted on 28. March 2010 by Vince Giuliano

In the recent blog entry SIRT1, mTOR, NF-kappaB and resveratrol, I pointed out how “three different theories of longevity seem to be collapsing into one: 1. suppression of mTOR signaling, 2. activation of SIRT1, and 3. inhibition of expression of … Continue reading →

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Visit with Leonard Guarante

Posted on 26. March 2010 by Vince Giuliano

A few days ago I visited Leonard Guarante, Director of the Glenn Laboratory for the Science of Aging at MIT and pioneer in the investigation of sirtuins and their longevity properties.  The lead line of the Laboratory’s web site is … Continue reading →

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SIRT1, mTOR, NF-kappaB and resveratrol

Posted on 24. March 2010 by Vince Giuliano

Among the few interventions that demonstrably extend lifespans across multiple species besides calorie restriction are 1. inhibition of the mTOR pathway, 2. the activation of sirtuins such as via calorie restriction or substances such as resveratrol, and 3. Inhibition of … Continue reading →

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Cell import and export traffic control signaling

Posted on 22. March 2010 by Vince Giuliano

Mechanisms for getting stuff into and out of cells are of great importance.  A new item of research came to my attention related to substance-trafficking that goes on within cells and across cell membrane barriers.  It has relevancy in terms … Continue reading →

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Telomeres and telomerase in Induced Pluripotent stem cells – not what we thought

Posted on 18. March 2010 by Vince Giuliano

An important new research article appeared yesterday, in the online edition of Future Medicine: Spontaneous reversal of the developmental aging of normal human cells following transcriptional reprogramming. The study is important because it contradicts an important earlier assumption about induced … Continue reading →

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Recent diabetes-related clinical trials

Posted on 15. March 2010 by Vince Giuliano

This blog entry reviews five very-recent clinical trials related to diabetes treatments, three that have failed and two that have succeeded.  I conclude by commenting on what I think are some underlying messages.  FAILED DIABETES-RELATED CLINICAL TRIALS I picked these … Continue reading →

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Fucoidan

Posted on 13. March 2010 by Vince Giuliano

Every once in a while I review a natural substance supplement.  This time its fucoidan, a complex sulfated polysaccharide (multi-sugar substance) found mainly in various species of brown seaweed.  Known for about 40 years for multiple health-giving biological activities, fucoidan … Continue reading →

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The social cost of Alzheimer’s disease and late-life dementia

Posted on 11. March 2010 by Vince Giuliano

My recent blog posting New views of Alzheimer’s disease and new approaches to treating it describes recent research relating to the disease and new understanding of what creates it.  This week the Alzheimer’s Association has released a new report that … Continue reading →

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Vitamin D3 and the immune response

Posted on 9. March 2010 by Vince Giuliano

Vitamin D is much in the news nowadays.  Over the last 10 years it has become increasingly clear that vitamin D plays several important roles beyond those involved in bone health.  Vitamin D presence or absence is implicated in several … Continue reading →

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