Author Archives: Vince Giuliano

About Vince Giuliano

Being a follower, connoisseur, and interpreter of longevity research is my latest career, since 2007. I believe I am unique among the researchers and writers in the aging sciences community in one critical respect. That is, I personally practice the anti-aging interventions that I preach and that has kept me healthy, young, active and highly involved at my age, now 96. I am as productive as I was at age 45. I don’t know of anybody else active in that community in my age bracket. In particular, I have focused on the importance of controlling chronic inflammation for healthy aging, and have written a number of articles on that subject in this blog. In 2014, I created a dietary supplement to further this objective. In 2019, two family colleagues and I started up Synergy Bioherbals, a dietary supplement company that is now selling this product. As of November 2025, I believe the longevity interventions I have already published in this blog and are being followed by me will easily get me to age 100 and somewhat beyond, still healthy, highly functional and working Further, I have been researching and will be pubishing about additional interventions which I expect will buy me several additional years of active healthy living. In earlier reincarnations of my career. I was Founding Dean of a graduate school and a full University Professor at the State University of New York, a senior consultant working in a variety of fields at Arthur D. Little, Inc., Chief Scientist and C00 of Mirror Systems, a software company, and an international Internet consultant. I got off the ground with one of the earliest PhD's from Harvard in a field later to become known as computer science. Because there was no academic field of computer science at the time, to get through I had to qualify myself in hard sciences, so my studies focused heavily on quantum physics. In various ways I contributed to the Computer Revolution starting in the 1950s and the Internet Revolution starting in the late 1980s. I am now engaged in doing the same for The Longevity Revolution. I have published something like 200 books and papers as well as over 430 substantive.entries in this blog, and have enjoyed various periods of notoriety. If you do a Google search on Vincent E. Giuliano, most if not all of the entries on the first few pages that come up will be ones relating to me. I have a general writings site at www.vincegiuliano.com and an extensive site of my art at www.giulianoart.com. Please note that I have recently changed my mailbox to vegiuliano@agingsciences.com.

Telomeres and telomerase in Induced Pluripotent stem cells – not what we thought

An important new research article appeared yesterday, in the online edition of Future Medicine: Spontaneous reversal of the developmental aging of normal human cells following transcriptional reprogramming. The study is important because it contradicts an important earlier assumption about induced … Continue reading

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Recent diabetes-related clinical trials

This blog entry reviews five very-recent clinical trials related to diabetes treatments, three that have failed and two that have succeeded.  I conclude by commenting on what I think are some underlying messages.  FAILED DIABETES-RELATED CLINICAL TRIALS I picked these … Continue reading

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Fucoidan

Every once in a while I review a natural substance supplement.  This time its fucoidan, a complex sulfated polysaccharide (multi-sugar substance) found mainly in various species of brown seaweed.  Known for about 40 years for multiple health-giving biological activities, fucoidan … Continue reading

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The social cost of Alzheimer’s disease and late-life dementia

My recent blog posting New views of Alzheimer’s disease and new approaches to treating it describes recent research relating to the disease and new understanding of what creates it.  This week the Alzheimer’s Association has released a new report that … Continue reading

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Vitamin D3 and the immune response

Vitamin D is much in the news nowadays.  Over the last 10 years it has become increasingly clear that vitamin D plays several important roles beyond those involved in bone health.  Vitamin D presence or absence is implicated in several … Continue reading

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Sestrins, longevity and cancers

A recent research report indicates that sestrin proteins can inhibit age-related pathologies in fruit flies and contribute to their longevity.  The genes and biological pathways involved exist also in humans.  This blog post reviews what the sestrin genes are, what … Continue reading

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BDNF gene – personality, mental balance, dementia, aging and epigenomic imprinting

BDNF stands for brain-derived neurotrophic factor, the protein generated by the BDNF gene, a substance that has been drawing a lot of attention recently in neuropsychiatric research circles.  I review some basic facts about BDNF here, recent research on how … Continue reading

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DNA repair cleanup failure – a root cause for cancers?

New research suggests that the answer to the question is quite possibly.  This is a rather technial subject and I will get into it in stages.  Finally, I speculate a little on the possible importance of the new research. Repair … Continue reading

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Joy and sadness of aging – and the impacts of longevity

This blog post is philosophical rather than scientific in its thrust, having to do with what successful aging consists of, including successful passing away.  Aging offers certain benefits – as long as you don’t age so much that you get … Continue reading

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New views of Alzheimer’s disease and new approaches to treating it

Alzheimer’s disease (AD) is a progressive and fatal disease affecting as many as 5.2 million Americans, the fourth most common cause of death in developing nations.  There are various treatments for symptoms of AD but as of now there is … Continue reading

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