Category Archives: Uncategorized

New name – same blog

As a belated second-birthday present, I am giving this blog a new name – Aging Sciences, as you can see in the header.   Starting now the latest blog entry will be available online at www.agingsciences.com.  Nothing is lost and all … Continue reading

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The many faces of mTOR and rapamycin

The intent of this blog entry is to present a sampler of recent research relating to the mTOR pathway and the effects of rapamycin, focusing on recent and longevity-related results not covered in previous blog entries. Background Of course mTOR … Continue reading

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Evolution and the prospect for much longer lifespans – video blog

A previous video blog entry has the message that we are already evolving to live longer.  But, does evolution set a limit on our lifespans, pre-ordain when we will die so to speak? Please see these videos for views of … Continue reading

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Age reversal – video blog

Age reversal appears to be a subject for science fiction, like the alchemist’s vision of turning lead into gold.  Yet, it can be induced on the cellular level.  If fact, for certain of our cells aging-avoidance or age-reversal is absolutely … Continue reading

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We are evolving to live longer – video blog

Biological evolution has been traditionally viewed as due to mutations in genes.  However this kind of evolution can require hundreds of thousands or millions of years to take hold   Now we know that evolution can happen much faster, in as … Continue reading

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The many faces of folic acid

The actions of folic acid, vitamin B9 are multiple, complex, directly affect the epigenome, and the implications of folic acid supplementation are still not fully known.  Folic acid supplementation appears to be strongly recommended in some circumstances and dangerous in … Continue reading

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The evolution of my perspective as a longevity scientist

This blog entry is personal, about my history relevant to longevity science.   It tells a bit about my earlier history with health and longevity science.   And it describes how my views regarding longevity science have evolved during my years of … Continue reading

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Cancer, epigenetics and dietary substances

Green tea, olive oil, blueberries, garlic and broccoli are among foods that work to reverse epigenetic changes that create susceptibility to cancers. A number of recent research publications relate to complex epigenetic conditions that lead to cancers – conditions that … Continue reading

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JDP2 – linking epigenetic modifications, stem cell differentiation, cell senescence, cell stress response, and aging

Important research published in late 2010 and 2011 relates to a protein JDP2 that plays a key role in cell-cycle processes.   JDP2 is involved with epigenetic modifications to histones relevant to age-related changes in stem cell differentiation and cell senescence.  … Continue reading

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US falling behind in longevity increases – why?

The US is falling behind other advanced countries in longevity gains.  This is the essential content of stories that appeared this week in almost every major newspaper.  The stories are based on a carefully-crafted study released by the National Academy … Continue reading

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