Category Archives: Uncategorized

Half glass of wine a day – good for longevity or bad because of increased cancer risk?

The answer depends on the study.  As far back as 1997, epidemiological studies suggested that moderate regular consumption of wine, red wine in particular, was associated with decreased risk of ischemic heart disease death(ref).   Then there is the often-cited 2007 … Continue reading

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Individual DNA testing

Major future leaps in longevity will most likely result from developments in molecular biology and genomics.  And, on a practical level individual DNA testing will sooner or later play a major role simply because our genomes are different.  After several … Continue reading

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P53 gene, normal and mutant, in the news

I have mentioned the P53 tumor-suppressor gene a number of times in my Anti-Aging Firewalls treatise, for example pointing out that  “Resveratrol and curcumin activate the P53 gene in many strains of cancer cells, leading them to commit apoptosis.”  Today’s … Continue reading

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Another longevity-related biochemical pathway

Another cross-species pathway has been discovered that allows interventions to lengthen life in primitive organisms, C. elegans nematode worms in this case.  The pathway is related to the hypoxic response, how cells respond to protect themselves when there is insufficient … Continue reading

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Human heart muscle cell renewal

The conventional wisdom has been that cell division in heart muscle cells (cardiomyocytes) stops at or shortly after birth and that the cardiomyocytes of an 80 year-old are the same ones he started out with.  The technology of radioactive carbon-dating … Continue reading

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Scientific integrity and advertising on my sites

It has been pointed out to me that this Blog and my Anti-Aging Firewalls treatise sites are now experiencing enough Internet traffic that I could generate revenue by accepting advertisements such as for proprietary dietary supplements, health cures, anti-aging treatments, … Continue reading

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US Army longevity research

Longevity research keeps showing up in unexpected places.  The US Army is pursuing research related to the third theory of aging in my Anti-Aging firewalls treatise, Mitochondrial Damage. They have an anti-aging research program called “Optimized Human Performance: Mitochondrial Energetics” … Continue reading

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“If you think you can do a thing or think you can’t do a thing, you’re right.” — Henry Ford

Whatever else you may think about Henry Ford, I think you will agree he knew what he wanted and in large part got it.  I spent most of yesterday with cousins in Greenfield Village, a large historical theme park founded … Continue reading

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Dr. Jekyll and Mr. Hyde proteins

A number of proteins in the body play dual roles with respect to longevity – negative roles in some circumstances and good roles under other circumstances.  I mention three substances in this regard: VEGF, telomerase and P16(Ink4a). –         VEGF stands … Continue reading

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Longevity – the sad personal side of it

Pushing on 80 I am still quite young compared to my intended target age.  But I am already experiencing a major downside of longevity – and that is experiencing the sadness of death or debilitating illness of dear relatives and … Continue reading

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