Blog Archives

By Vince Giuliano The press has recently picked up heavily on work by Mayo Clinic researchers related to reversal of cell-senescence in-vivo via inhibition of expression of the protein p16(Ink4a).  The research has been heralded by such headlines as Cell … Continue reading →

Previously I have written about the roles of glia and microglia in Alzheimer’s disease and in spinal cord injury.  This blog entry reports on recent research which documents the importance of glial pathology as a general underlying factor in essentially … Continue reading →

This blog entry unifies three themes that have repeatedly been expressed in this blog: 1.  The possibility of extending lives via using “rebooted” cells, that is induced pluripotent stem cells (iPSCs), 2.  the key role of epigenetic factors in determining … Continue reading →

By Vince Giuliano The last few months have seen the continuation of an extraordinary pace of research related to induced pluripotent stem cells (iPSCs), a technology stream that has been widely heralded as key for organ regeneration, for regenerative medicine, … Continue reading →

By Brendan Hussey  In my previous post, The Nuclear DNA Damage/Mutation Theory of Aging, I presented evidence that inequities in cell maintenance between germ and somatic cells are a major causal factor for the deterioration of somatic cells resulting in … Continue reading →

There is a substantial amount current research on cat’s claw (uncaria tomentosa, in Spanish Uña de Gato), a herb imported from the Peruvian Amazon.  This blog entry documents some of the properties of this remarkable substance and a number of … Continue reading →

By Vince Giuliano Mainline scientific theories may have long lifespans but are inevitably overturned as accumulating evidence renders them obsolete and brings alternative theories to the fore.  We saw this in physics over 100 years ago when relativity theory and … Continue reading →

By Vince Giuliano The human immune system provides our defenses against pathogens. This blog entry focuses on research on T-cells. a family of cells in the immune system.  The research is relevant to aging because it challenges the traditional view … Continue reading →

By Victor Most popular discussions of antioxidants are based on an outdated view of free radicals as evil, toxic compounds, ones which cause chain reactions of destructive damage culminating in degenerative diseases and aging.  Research in recent years has revealed … Continue reading →

By Victor The August 2011 PLoS Medicine article, Legal Remedies for Medical Ghostwriting discusses legal approaches to combat the prevalent practice of published “academic” studies, which are actually ghostwritten at the behest of pharmaceutical companies.  That is right, in many … Continue reading →