Author Archives: Vince Giuliano

About Vince Giuliano

Being a follower, connoisseur, and interpreter of longevity research is my latest career, since 2007. I believe I am unique among the researchers and writers in the aging sciences community in one critical respect. That is, I personally practice the anti-aging interventions that I preach and that has kept me healthy, young, active and highly involved at my age, now 96. I am as productive as I was at age 45. I don’t know of anybody else active in that community in my age bracket. In particular, I have focused on the importance of controlling chronic inflammation for healthy aging, and have written a number of articles on that subject in this blog. In 2014, I created a dietary supplement to further this objective. In 2019, two family colleagues and I started up Synergy Bioherbals, a dietary supplement company that is now selling this product. As of November 2025, I believe the longevity interventions I have already published in this blog and are being followed by me will easily get me to age 100 and somewhat beyond, still healthy, highly functional and working Further, I have been researching and will be pubishing about additional interventions which I expect will buy me several additional years of active healthy living. In earlier reincarnations of my career. I was Founding Dean of a graduate school and a full University Professor at the State University of New York, a senior consultant working in a variety of fields at Arthur D. Little, Inc., Chief Scientist and C00 of Mirror Systems, a software company, and an international Internet consultant. I got off the ground with one of the earliest PhD's from Harvard in a field later to become known as computer science. Because there was no academic field of computer science at the time, to get through I had to qualify myself in hard sciences, so my studies focused heavily on quantum physics. In various ways I contributed to the Computer Revolution starting in the 1950s and the Internet Revolution starting in the late 1980s. I am now engaged in doing the same for The Longevity Revolution. I have published something like 200 books and papers as well as over 430 substantive.entries in this blog, and have enjoyed various periods of notoriety. If you do a Google search on Vincent E. Giuliano, most if not all of the entries on the first few pages that come up will be ones relating to me. I have a general writings site at www.vincegiuliano.com and an extensive site of my art at www.giulianoart.com. Please note that I have recently changed my mailbox to vegiuliano@agingsciences.com.

P53 gene, normal and mutant, in the news

I have mentioned the P53 tumor-suppressor gene a number of times in my Anti-Aging Firewalls treatise, for example pointing out that  “Resveratrol and curcumin activate the P53 gene in many strains of cancer cells, leading them to commit apoptosis.”  Today’s … Continue reading

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Another longevity-related biochemical pathway

Another cross-species pathway has been discovered that allows interventions to lengthen life in primitive organisms, C. elegans nematode worms in this case.  The pathway is related to the hypoxic response, how cells respond to protect themselves when there is insufficient … Continue reading

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Human heart muscle cell renewal

The conventional wisdom has been that cell division in heart muscle cells (cardiomyocytes) stops at or shortly after birth and that the cardiomyocytes of an 80 year-old are the same ones he started out with.  The technology of radioactive carbon-dating … Continue reading

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Scientific integrity and advertising on my sites

It has been pointed out to me that this Blog and my Anti-Aging Firewalls treatise sites are now experiencing enough Internet traffic that I could generate revenue by accepting advertisements such as for proprietary dietary supplements, health cures, anti-aging treatments, … Continue reading

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US Army longevity research

Longevity research keeps showing up in unexpected places.  The US Army is pursuing research related to the third theory of aging in my Anti-Aging firewalls treatise, Mitochondrial Damage. They have an anti-aging research program called “Optimized Human Performance: Mitochondrial Energetics” … Continue reading

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“If you think you can do a thing or think you can’t do a thing, you’re right.” — Henry Ford

Whatever else you may think about Henry Ford, I think you will agree he knew what he wanted and in large part got it.  I spent most of yesterday with cousins in Greenfield Village, a large historical theme park founded … Continue reading

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Dr. Jekyll and Mr. Hyde proteins

A number of proteins in the body play dual roles with respect to longevity – negative roles in some circumstances and good roles under other circumstances.  I mention three substances in this regard: VEGF, telomerase and P16(Ink4a). –         VEGF stands … Continue reading

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Longevity – the sad personal side of it

Pushing on 80 I am still quite young compared to my intended target age.  But I am already experiencing a major downside of longevity – and that is experiencing the sadness of death or debilitating illness of dear relatives and … Continue reading

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Secrets to longevity

There seems to be no end to news stories about people 100 and over reporting their secrets to longevity.  Here is a sample from today’s news: :·        Being kind to people and eating healthy food (age 102) ·        Exercise (age … Continue reading

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“Sonic hedgehog requires interactions with proteoglycans to achieve cell proliferation, but not tissue patterning”

What the heck does this mean?  It means an additional jigsaw-puzzle piece of knowledge relevant to the 14th theory of aging in my Anti-Aging Firewalls treatise, which is Decline in Adult Stem Cell Differentiation.  In this instance Sonic hedgehog (Shh) … Continue reading

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