Category Archives: Uncategorized

Skin Cancer immunotherapies

Immunotherapies are ones that mobilize the body’s own immune system defense against disease processes.  This blog entry is about immunotherapies for skin cancers, focusing on an effective older one known as imiquimod or by its trade name aldara, and a … Continue reading

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Contrarian research findings: newly-identified aging villain substances; calorie restriction longevity is not due to calorie restriction

Recent publications have surfaced substances that may contribute to aging including favorites used to extend longevity.  Also, it has cast light on longevity due to calorie restriction suggesting that what counts is not the calories as much as the food … Continue reading

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Turning P53 on in cancer cells

The P53 protein provides a first line of defense against cancers, causing cancer cells to commit apoptosis.  “p53 (also known as protein 53 or tumor protein 53), is a tumor suppressor protein that in humans is encoded by the TP53 … Continue reading

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Diabetes Part 2: Lifestyle, dietary and supplement interventions

In the post Diabetes Part I: Biology and molecular dynamics of diabetes, I described a pathological biomolecular process through which diabetes arises from obesity or metabolic syndrome.  I also provided reference links to publications amplifying on the details of the … Continue reading

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Diabetes Part I: Biology and molecular dynamics of diabetes

This is the first of two related blog posts on diabetes.  Here I review the nature of diabetes, and a commonly occurring biomolecular processes underlying the development of Type 2 diabetes.  I quote from several recent research papers relating diabetes … Continue reading

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Alzheimer’s disease studies validate anti-aging firewalls suggestions

At the still-ongoing (as of July 12, 2010) meeting of the American Alzheimer’s Association in Honolulu, four different papers were presented that  validate components of the anti-aging firewalls regimen suggested in my treatise Anti-Aging Firewalls – The Science and Technology … Continue reading

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Induced pluripotent stem cells – developments on the road to big-time utilization

I have written about developments relating to cell reprogramming and induced pluripotent stem cells (iPSCs) in several previous blog posts, the most recent including A near-term application for iPSCs – making cell lines for drug testing, Induced pluripotent stem cells … Continue reading

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Three years exploring longevity science

Longevity science had been a hobby for me for a long time and about 3 years ago I decided to pursue it as a new full-time career.  I put the first version of my treatise Anti-Aging Firewalls – The Science … Continue reading

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HSP70 to the rescue

Hormesis is a process through which moderate stress induces a body response that is protective against insults, confers health and possibly even longevity benefits.  The process of hormesis is thought to be mediated primarily via heat shock proteins (HSPs).  An … Continue reading

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AMPK and longevity

The AMPK signaling pathway is one that is increasingly being viewed as playing a central role in metabolism and growth(ref). And that pathway appears to have a lot to do with longevity.  In fact, it is possible that some degree … Continue reading

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