Category Archives: Uncategorized

Age-related cognitive decline: focus on interventions

In previous blog entries and in my longevity treatise, I have discussed factors involved in age-related decline in memory and cognitive functioning.  This blog entry is concerned with research findings that suggest practical approaches to slowing or possibly reversing such … Continue reading

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Health and longevity benefits of plant polyphenols – focus grape seed extract

As the productivity of conventional drug discovery methods declines, there is a growing interest in the use of natural dietary substances for the prevention and treatment of multiple disease conditions.  In previous blog entries I have discussed a number of … Continue reading

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Observations on Lyme Disease

“Lyme disease is the most common vector-borne illness in the United States and is also endemic in Europe and Asia(ref).”   Recently, a close member of my family contracted an acute case of Lyme Disease (LD), leading me to review the … Continue reading

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Aging as a genomic-epigenomic dance

By Vince Giuliano Much of what we observe in aging appears to come about through accumulated genomic damage, or through aging-related epigenomic mechanisms. This blog entry explores the relationship of genomics to epigenomics with respect to diseases and aging. Some … Continue reading

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Kinase Inhibition – A Magic Bullet?

By Victor Protein kinases are enzymes which transfer phosphate groups from donors such as ATP to proteins in a process call “phosphorylation”. This process is usually reversible; phosphatases are the enzymes which “dephosphorylate” or remove phosphate groups from proteins. Each … Continue reading

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Longevity of stem cells and the roles of stem cells in aging

By Vince Giuliano This blog entry is about somatic stem cells, the natural kind that reside in adult bodies, the factors that affect their health and longevity, the changes they undergo in the process of aging, and the roles they … Continue reading

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Update on induced pluripotent stem cells

By Vince Giuliano The last seven months have seen a great deal of research related to and induced pluripotent stem cells (iPSCs) and cell reprogramming. This blog post is devoted to some important perspectives that have emerged resulting from that … Continue reading

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Getting back to serious research and writing

The last three weeks has seen a series of blog problems and a hiatus of new postings.  Now the last of these problems are being straightened out and I and my colleague Victor are getting back to serious writing. Here … Continue reading

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Spam update

By Vince – admin Our blog has been under a massive robot spam comment attack over the last four days.  We received, I estimate, 500 comments and all but a few were spam.  These inundated my personal mail and attached … Continue reading

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Strange characters in past blog posts

From Vince, Admin After we switched to the new blog software, many past blog entries show up with strange interspersed characters such as at the end of sentences and †where an apostrophe (‘) should be.  Although these symbols are … Continue reading

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