Category Archives: Uncategorized

Focus on phytosubstances – amazing properties of epimedium and icariin

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By Vince Giuliano Icariin is the active flavinoid substance in the traditional Chinese medicinal herb Epimedium brevicornum Maxim.  Icariin can be derived from several species of plants in the Epimedium family.  These plants are known most popularly as Horny Goat … Continue reading

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Blue light, sleep, mental alertness and health

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By Vince Giuliano We are being exposed to a lot more blue and ultraviolet light in recent years, especially at night.  This is due to 1. fluorescent bulbs replacing incandescent bulbs in homes and workspaces, especially “daytime” spectrum bulbs, 2. … Continue reading

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Gut microbiota, probiotics, prebiotics and synbiotics – keys to health and longevity

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By Vince Giuliano To take care of your own health you have to take care of about a hundred trillion other living entities.  Each of us is in close relationship with that many micro-organisms belonging to hundreds of different species … Continue reading

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The pivotal role of Nrf2. Part 3 – Part 3 – Is promotion of Nrf2 expression a viable strategy for human human healthspan and lifespan extension?

By Vince Giuliano This is the third of three blog entries relating to the Nrf2 pathway.  The first blog entry The pivotal role of Nrf2. Part 1 – a new view on the control of oxidative damage and generation of … Continue reading

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The pivotal role of Nrf2. Part 2 – foods, phyto-substances and other substances that turn on Nrf2

By Vince Giuliano – updated Feb 8 and Feb 9, 2012 This is the second of three blog entries relating to the Nrf2 pathway.  The previous blog entry The pivotal role of Nrf2. Part 1 – a new view on … Continue reading

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The pivotal role of Nrf2. Part 1 – a new view on the control of oxidative damage and generation of hormetic effects

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The old free radical theory if aging is dead.  And, consuming excessive pure antioxidant supplements can be dangerous rather than health producing – see the blog entry End of the free radical theory of aging and negative consequences of indiscriminante … Continue reading

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Circadian Regulation, NMN, Preventing Diabetes, and Longevity

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By Victor Circadian Regulation is a fascinating topic with ties to many issues involved in antiaging research, including the regulation of stem cell populations.(See The circadian molecular clock creates epidermal stem cell heterogeneity, Biological Clock Controls Activation of Skin Stem … Continue reading

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Alternate-day Fasting – a better alternative

By Victor For humans who wish to live long lives, alternative-day fasting may be a better approach than following a restricted calorie diet.  The approach avoids premature induction of frailty most likely by periodically inhibiting myogenesis which encourages replenishment of … Continue reading

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Dietary factors and dementia – Part 3: plant-derived substances that can make a difference

By Vince Giuliano Like the previous two blog entries Dietary factors and dementia – Part 1: important recent researchandDietary factors and dementia Part 2: possible interventions, this blog entry is focused on research during the last two years relating dietary … Continue reading

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Dietary factors and dementia Part 2: possible interventions

By Vince Giuliano The first blog entry in this series of three Dietary factors and dementia – Part 1: important recent research dealt with research on a variety of subtopics such as the value of the relationship of dementia to … Continue reading

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