Search Results for: radiation hormesis

US falling behind in longevity increases – why?

The US is falling behind other advanced countries in longevity gains.  This is the essential content of stories that appeared this week in almost every major newspaper.  The stories are based on a carefully-crafted study released by the National Academy … Continue reading

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SIRT3 research – tying together knowledge of aging

Those of you who have put together jigsaw puzzles know that every once in a while a piece is found that links together several seemingly unrelated chunks of the puzzle.  The sirtuin SIRT3 is doing that for several chunks of … Continue reading

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Genomic stability, DNA repair and the sirtuin SIRT6

One theory of aging is that the genome and other DNA of an organism accumulate increasing numbers of errors with age and that these errors are responsible for the macroscopic phenomenon we call “aging.” See the second theory of aging … Continue reading

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HSP70 to the rescue – But, no, no! That’s not what we want for cancer cells

The July 2010 blog entry HSP70 to the rescue describes how heat shock protein 70 (HSP70) works to promote survival of cells under stress and provides examples of the positive hormetic effects of this chaperone protein.  For example HSP70 is … Continue reading

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Valproic acid – The phoenix drug arises again

The chemical valproic acid has been around for a very long time.  It was first synthesized in 1882 and for a great many years it seemed to be not very useful. However, over its 128 year history valproic acid has … Continue reading

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