Blog Archives

Response to Jim Watson’s wager challenge

Image source This blog entry is in response to the wager challenge in Jim Watson’s post Aging science wager challenges and prizes open to readers of 8 April, 2013.  As you will recall, $2.00 is the total at stake. Normally, … Continue reading

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Autophagy – the housekeeper in every cell that fights aging

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By James P Watson and Vince Giuliano Background and introduction There is a wide variety of genetic manipulations, pharmacologic manipulations, and nutrient manipulations that have been shown to alter lifespan in model organisms.  These include caloric restriction, “loss of function” … Continue reading

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Aging science wager challenges and prizes open to readers.

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Image source Frequent readers of this blog know that James P Watson (Jim) is a colleague and significant contributor to this blog.  Jim recently sent me an e-mail offering to make personal wager bets with me on two questions related … Continue reading

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The Prospects that Emerging Science Offers Us for Longer Healthy Lifespans

On March 25 2013, I gave a presentation “The Prospects that Emerging Science Offers Us for Longer Healthy Lifespans” as part of the Kopriva Science Seminar series at Montana State University.  Thanks in part to good newspaper publicity, The Hager … Continue reading

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Announcement – Vivace Associates

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  A small group of key colleagues and I have formed a new consulting business, Vivace Associates.  Our target clients are all organizations concerned with the cost and efficiency of health care – health insurance companies, governments and government agencies, … Continue reading

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Multifactorial hormesis II – Powerpoint presentation

This blog entry contains the PowerPoint presentation I gave in Honolulu at the Hawaii Institute for Molecular Education Symposium Investigating the Future of Medicine which was Webcast on March 16, 2013.  The presentation is more graphical and less technical than the … Continue reading

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Sarcopenia – the Age-related Loss of Muscle Mass and Function – Part I: Pathways and factors

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By Victor, with contributions by Vince Giuliano Satellites in Muscle Part I It is well established that the maintenance of skeletal muscle mass contributes significantly to disease prevention and avoidance of falls and many other problems that degrade quality of … Continue reading

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Mitochondria Part 2: Mitochondrial Responses to Stress: Mitochondrial Signaling: Survival and Death Pathways

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Written by James Watson, with major contributions by Vince Giuliano Introduction – Mitochondrial Roles in the Cell This is the second part in a series of blog entries examining the roles of mitochondria in key biological activities.  For additional background … Continue reading

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Microtubules, the intra-cellular transport system, health and longevity

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Microtubules, the intra-cellular transport system, health and longevity By Vince Giuliano Image source Microtubules play important and ever-changing structural roles in cells, play key roles in  embryo development and cell division, are the basis for the intra-cellular molecular transport system, … Continue reading

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Multifactorial hormesis – the theory and practice of maintaining health and longevity

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By Vince Giuliano and James P Watson This blog entry generalizes on the concept of hormesis, discusses the multiple pathways through which hormesis takes place, and suggests a myriad of ways that ordinary people can take advantage of hormesis to … Continue reading

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