Anti-Aging Firewalls Version 1.9 – state of progress

It is now approximately 11 months since I posted the first version of the Anti-Aging Firewalls treatise and it is interesting to identify how the current version of the treatise (which might  be considered to be Version 1.9) is different from the original one.  I have been updating the treatise frequently, sometimes weekly, sometimes daily.  There have been at least a dozen major upgrades and additions over the period including one made today which includes a new section on the Relationships among the theories of aging. Compared to the original, the treatise now:

·        Embodies three additional theories of aging beyond the original 11 ones, Telomere Shortening and Damage, Programmed Epigenomic Changes, and Decline in Adult Stem Cell Differentiation,

·        Embodies significant discussions throughout on the relationships among the theories of aging including the new section on that topic,

·        Has a summary section describing the Combined Lifestyle Regimen,

·        Has a revised  Combined Dietary Supplement regimen with a few substances added to the original list, a deletion or two and revised dosages for a few supplements,

·        Embodies considerable discussion on selected topics including stem cell differentiation, neurogenesis, telomerase-related developments and the role of NF-kappaB,

·        Provides a much larger number of research literature research links backing up key points,

·        Provides considerable more discussion on the roles of certain of the dietary supplements, and

·         Embodies a series of technical notes on subjects like protein folding, telomerase binding proteins, and the firewall against osteoarthritis

These changes reflect two factors: first, developments reported in the research literature during the 11-month period that came to my attention, and second, continuing increase in my own awareness and comprehension.  I believe the net result is improvement in the scientific integrity and comprehensiveness of the treatise.  This Blog, started in January 2009, now includes some 55 major postings and is an important complement to the treatise.  Specifically, I have explored certain topics here that are peripheral to the main treatise, topics like epigenomics, population longevity studies, the economics of longevity and the prospects for living very long. A complete list of postings can be found by clicking on the left on Site Admin and then on the Manage tab.  You might have to be a registered user and login in order to access the entire list.

About Vince Giuliano

Being a follower, connoisseur, and interpreter of longevity research is my latest career. I have been at this part-time for well over a decade, and in 2007 this became my mainline activity. In earlier reincarnations of my career. I was founding dean of a graduate school and a university professor at the State University of New York, a senior consultant working in a variety of fields at Arthur D. Little, Inc., Chief Scientist and C00 of Mirror Systems, a software company, and an international Internet consultant. I got off the ground with one of the earliest PhD's from Harvard in a field later to become known as computer science. Because there was no academic field of computer science at the time, to get through I had to qualify myself in hard sciences, so my studies focused heavily on quantum physics. In various ways I contributed to the Computer Revolution starting in the 1950s and the Internet Revolution starting in the late 1980s. I am now engaged in doing the same for The Longevity Revolution. I have published something like 200 books and papers as well as over 430 substantive.entries in this blog, and have enjoyed various periods of notoriety. If you do a Google search on Vincent E. Giuliano, most if not all of the entries on the first few pages that come up will be ones relating to me. I have a general writings site at and an extensive site of my art at Please note that I have recently changed my mailbox to
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