New-science approaches to detecting, preventing and curing cancers

Posted on 16. December 2009 by Vince Giuliano

I have covered a number of new-science approaches to detecting, preventing or curing cancers in this blog and in other writings.  The context was set in an early blog entry From four-pound hammer to smart molecules – on cancer treatments.  Here is a listing of the new approaches and twists on old ones, citing relevant blog and writing entries:

*  DNA demethylation:  See DNA demethylation – a new way of coming at cancers.  Also Homicide by DNA methylation, and Embryonic Stem cell research news.  In my treatise see the candidate theory of aging Epigenomic Changes in DNA Methylation and Histone Acetylation and the blog entry Epigenetics, Epigenomics and Aging.

*  Use of terminator stem cells:  See Terminator stem cells in the early pipeline.  See also Trojan-horse stem cells might offer an important new cancer therapy, and Progress in fighting glioblastoma.

*  Using TRAIL to kill cancer cells: See On the TRAIL of a selective cancer treatment.  Also note Terminator stem cells in the early pipeline.

*  Keeping telomeres long:   See Revisiting telomere shortening yet-again.  The discussion in the treatise section Telomere Shortening and Damage is relevant for background.

*  Telomerase activation affect on cancer stem cells:  See Extra-telomeric benefits of telomerase – good news for telomerase activators. 

*  Gene therapy: See for example A Fascinating dance of death and life – Fas, FasL and diseases. 

*  Targeting the Factor 5A1 gene: See Senesco and the Factor 5A1 gene

* Inhibition of expression of NF-kappaB:  See in my treatise discussions in the Susceptibility to Cancers Firewall and in the Programmed Epigenomic Changes Firewall.

*  Taking advantage of the NRG1 GENE:  See The NRG1 Gene – an important new tumor suppressor gene?, Also see DNA demethylation – a new way of coming at cancers

*  Targeting the Nrf2 gene: see Nrf2 and cancer chemoprevention by phytochemicals.  Also Phytochemicals – focus on caffeic acid and Health and longevity benefits of dark chocolate.

* Targeting cancer stem cells:  see News on disabling cancer stem cells, Big Pharma is targeting cancer stem cells, Update on cancer stem cells, and On cancer stem cells.

*  Plant-derived substances:   See Progress in fighting glioblastoma re curcumin,  see Cordyceps militaris and cancer, and Blueberries and health – the research case.

*  Chemotherapy combinations and substances in clinical trials for lymphomas: see Autoimmune diseases and lymphoma – Part III: focus on lymphomas 

*  Cancer immunotherapy:  See Dendritic cell cancer immunotherapy 

*  DHMEQ:  See More on DHMEQ and a no-no mind bender and DHMEQ.

* Prevention of oncogenic radiation-induced DNA damage:  See my paper Protection Against Radiation – The Second Line of Defense.

For the time being it appears that the multiple forms of cancer offer multiple challenges and that multiple approaches  will be needed to deal with these challenges.  Thus, each of the above approaches and others yet may turn out to have their roles. I will continue to monitor these and other emerging developments.

About Vince Giuliano

Being a follower, connoisseur, and interpreter of longevity research is my latest career, since 2007. I believe I am unique among the researchers and writers in the aging sciences community in one critical respect. That is, I personally practice the anti-aging interventions that I preach and that has kept me healthy, young, active and highly involved at my age, now 93. I am as productive as I was at age 45. I don’t know of anybody else active in that community in my age bracket. In particular, I have focused on the importance of controlling chronic inflammation for healthy aging, and have written a number of articles on that subject in this blog. In 2014, I created a dietary supplement to further this objective. In 2019, two family colleagues and I started up Synergy Bioherbals, a dietary supplement company that is now selling this product. In earlier reincarnations of my career. I was Founding Dean of a graduate school and a full University Professor at the State University of New York, a senior consultant working in a variety of fields at Arthur D. Little, Inc., Chief Scientist and C00 of Mirror Systems, a software company, and an international Internet consultant. I got off the ground with one of the earliest PhD's from Harvard in a field later to become known as computer science. Because there was no academic field of computer science at the time, to get through I had to qualify myself in hard sciences, so my studies focused heavily on quantum physics. In various ways I contributed to the Computer Revolution starting in the 1950s and the Internet Revolution starting in the late 1980s. I am now engaged in doing the same for The Longevity Revolution. I have published something like 200 books and papers as well as over 430 substantive.entries in this blog, and have enjoyed various periods of notoriety. If you do a Google search on Vincent E. Giuliano, most if not all of the entries on the first few pages that come up will be ones relating to me. I have a general writings site at www.vincegiuliano.com and an extensive site of my art at www.giulianoart.com. Please note that I have recently changed my mailbox to vegiuliano@agingsciences.com.
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4 Responses to New-science approaches to detecting, preventing and curing cancers

  1. curious sle says:
    17. December 2009 at 16:29

    Hi, in your treatise on DNA damage you fail to mention AC-11, a cat’s claw extract that upregulates DNA repair tremendously. In hope this is of use to you…

    Regards
    curious.sle

  2. admin says:
    17. December 2009 at 19:55

    Hi curious sle

    Let me look into that. A friend gave me 3 bottles of cat’s claw extract and I have not known what it is or what to do with it.

    Vince

  3. Vincent Giuliano says:
    7. December 2011 at 21:33

    Curious SLE

    Your comment on Cat’s Claw stimulated me to generate the blog post http://www.anti-agingfirewalls.com/?s=Cat%27s+claw A fairly thorough treatment of the subject. I also have started taking it as a supplement.

    Vince

  4. Pingback: New, emerging and potential treatments for cancers: Part 2 – focus on anti-cancer interventions that simultaneously address multiple growth pathways | AGING SCIENCES – Anti-Aging Firewalls

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