Blog Archives

Genetic and epigenetic factors in cancer, cellular senescence and the light and dark sides of exosome communications in cancer

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By James P Watson with assistance by Vince Giuliano This blog entry looks at the genetic and epigenetic factors in cancer.  The news here is basically good – epigenetic transformations seem in many cases to be upstream of genetic mutations … Continue reading

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Circular RNA – The RNA Story is coming Full Circle” – “Exon Skipping”explains Atherosclerosis and possibly aging

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By James P Watson with contributions and editing by Vince Giuliano This blog entry tells two stories.  The first story is that of circular RNAs.  Once we thought that any important DNA was located in the nucleus of cells on … Continue reading

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More on the xenohormetic live food hypothesis – synergies among polyphenols, additional post-harvest plant stressors and stress responses, plant polyphenol transcription factors, and more

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By James P Watson  I believe the the message of the previous blog entry Health through stressing fruits and vegetables – the Xenohormetic Live Food Hypothesis by Vince and Melody is worthy of acclaim.  As so frequently happens, it fueled … Continue reading

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Health through stressing fruits and vegetables – the Xenohormetic Live Food Hypothesis (updated)

By Vince Giuliano and Melody Winnig Update , October 17, 2013:  The purpose of this blog entry is to lay out a hypothesis that could turn out to be very significant for health and longevity if it were practically applied. We … Continue reading

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Quorum Sensing Part 2 – Intra and inter-species molecular communications

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By Vince Giuliano Life depends on molecular messaging. Cells and organisms – simple ones like c-elegans and complicated ones like humans – are constantly exchanging internal molecular messages. These messages are critical for articulating development, tissue homeostasis, repairs of various … Continue reading

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Quorum sensing Part 1: quorum sensing inhibition via phytochemicals – a new approach against infectious diseases.

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By Vince Giuliano   Image source                                         Image source Among infectious bacteria, talk is not cheap. Quorum sensing (QS) is a fundamental biological process involving how cells in assemblages sense and communicate and cooperate with each other.  It applies to bacterial … Continue reading

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THE HORMESIS BARS

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A collection of stories and explanations by Jim Watson and Vince Giuliano The stories are fantasies about new kinds of bars that could possibly exist in the future.  The Hormesis Bars are ones where all the drinks produce stresses.  According … Continue reading

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PART 3: Slaying Two Dragons with the Sound of Silence: – How to Keep Your Repetitive DNA Turned Off with “3 Songs”: Sirtuins, Polycomb Proteins, and DNMT3. And a Master List of Drugs and Natural Compounds for Cancer Chemoprevention

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By James Watson (with some help from Vince Giuliano) Image source This is the Part 3 of a three-part series of blog entries on the epigenetic’s of cancer and aging and how those two deadly dragons can be seriously slowed … Continue reading

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PART 2: Slaying Two Dragons with One Hail of Stones: The Silencing Of Good Genes In Aging And Cancer – And How Polyphenols Can Prevent That

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 By James Watson (with editorial help from Vince Giuliano) Image source This is the Part 2 of a three-part series of blog entries on the epigenetic’s of cancer and aging and how those two deadly dragons can be seriously slowed … Continue reading

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PART 1: Slaying Two Dragons with One Stone – How to Prevent Cancer and Aging with the Same Strategy

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Image source By James Watson and Vince Giuliano This is the first part of a three-part series of blog entries on the epigenetic’s of cancer and aging and how those two deadly dragons can be seriously slow down or stopped … Continue reading

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