Alternate-day Fasting – a better alternative

By Victor For humans who wish to live long lives, alternative-day fasting may be a better approach than following a restricted calorie diet.  The approach avoids premature induction of frailty most likely by periodically inhibiting myogenesis which encourages replenishment of … Continue reading

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Dietary factors and dementia – Part 3: plant-derived substances that can make a difference

By Vince Giuliano Like the previous two blog entries Dietary factors and dementia – Part 1: important recent researchandDietary factors and dementia Part 2: possible interventions, this blog entry is focused on research during the last two years relating dietary … Continue reading

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Dietary factors and dementia Part 2: possible interventions

By Vince Giuliano The first blog entry in this series of three Dietary factors and dementia – Part 1: important recent research dealt with research on a variety of subtopics such as the value of the relationship of dementia to … Continue reading

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Dietary factors and dementia – Part 1: important recent research

By Vince Giuliano This is the first of three blog entries focusing on research during the last two years relating diet, dietary substances and supplements to late-onset dementias including Alzheimer’s disease (AD), and to the potential roles of such substances … Continue reading

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Focus on phytosubstances – Danshen root – amazing properties of salvia miltiorrhiza Bunge

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Salvia miltiorrhiza Bunge (Danshen root) is an important staple of traditional Chinese medicine that has long been used to treat a variety of illnesses including type-2 diabetes, cardiovascular and cerebrovascular diseases.  Strong research evidence such as that cited here indicates … Continue reading

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History and future directions for this blog – invitation for associate researchers/writers

Soon this blog will celebrate its third birthday.  So I pause here to discuss where it has been and is going.  I also issue a new invitation for applicants who may be interested in becoming associate researchers/writers for the blog. … Continue reading

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More about Klotho – spinner of the thread of life

I published an introduction to the remarkable “anti-aging gene” Klotho in the October 2009 blog entryKlotho anti-aging gene in the news, and a September 2010 update Klotho, phosphates, cola drinks and longevity.  Since then in little more than a year, … Continue reading

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CAR adoptive stem cell immunotherapy– an emerging new weapon against cancers and other incurable diseases

By Vince Giuliano There is current excitement about a new approach to using a person’s own immune system to fight and defeat otherwise incurable cancers: Adoptive immunotherapy, a technology that is currently the subject of multiple clinical trials.  Here, I … Continue reading

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Mechanisms and Effects of Dietary Restriction

By Victor In 1934, researchers at Cornell University discovered that laboratory rats fed a severely restricted diet lived up to twice as long as those fed a regular diet.  Subsequent research has confirmed the health and longevity benefits of dietary … Continue reading

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Latest p16(Ink4a) senescence-reversing research – an important but not game-changing contribution

By Vince Giuliano The press has recently picked up heavily on work by Mayo Clinic researchers related to reversal of cell-senescence in-vivo via inhibition of expression of the protein p16(Ink4a).  The research has been heralded by such headlines as Cell … Continue reading

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