Meeting notice – The Science and Technology of Longevity

By Vince Giuliano I am speaking on The Science and Technology of Longevity Thursday, June 16, 2016 in Palo Alto starting 7PM PDT. The event will be hosted by the Silicon Valley Health Institute, The talks are on The Prospects … Continue reading

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Part 5 of the NAD world: the conflicting roles of NAMPT – inflammation or rescue? Also Part 1 on a new series on inflammation

By James P Watson with commentary and assistance by Vince Giuliano Introduction by Vince Giuliano This blog entry relates another important story of what goes on in the NAD world. This is also the first entry of what I expect … Continue reading

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Coming in this blog

By Vince Giuliano and James P Watson This entry signals some intended changes in our blogging approach and lists some blog entries we plan to publish soon. A.  Changes in blogging approach We expect to go to shorter more- focused … Continue reading

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2016 meeting of the International Dose-response Society

Note by Vince Giuliano As has been the case in several previous years, I intend to attend the 2016 annual meeting of the International Dose-response Society which will be held on the Campus of the University of Massachusetts in Amherst … Continue reading

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Hutchinson-Gilford Progeria Syndrome – a disease of accelerated aging due to Alternative Splicing

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By James P Watson with editorial assistance and contributions from Vince Giuliano I.  WHY YOU SHOULD BE INTERESTED IN HUTCHINSON-GILFORD PROGERIA SYNDROME (HGPS) Summary: HGPS is a major clue to solving the “puzzle of aging” and the molecular mechanisms here … Continue reading

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Transposable DNA elements – Part 3 TEs and and other key mechanisms of evolution: incRNAs, A to I editing, alternative splicing and exonization

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By Vince Giuliano, with inspiration by Jim Watson                   Image source:  “These clusters of cells are 1 billion years old, the oldest to appear in freshwater/land ecosysems   Credit: Oxford University/Martin Brasier ”  … Continue reading

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Transposable DNA elements –- Part 2: The Self-copy Machines in Your Genes

By James P Watson with editorial and some content contribution by Vince Giuliano This is the second blog entry in a three-part series concerned with transposable DNA entries (TEs).  The Part 1 entry focused on basics of what TEs are, … Continue reading

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Transposable DNA elements – Part 1: basics and importance

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By Vince Giuliano, inspired by interaction by James P. Watson This is the first blog entry in a three-part series concerned with transposable DNA entries (TEs).  It focuses on basics of what TEs are, why they are important for us … Continue reading

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G-qaudruplexes

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By James P Watson with editorial help and selected contributions by Vince Giuliano Image source Human telomeric G-quadruplex structure  Introduction by Vince Giuliano If you are new to G-quadraplexes, I can appreciate reader resistance to confronting the intellectual challenge of … Continue reading

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The top 21Benefits of Meditation

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By James P Watson, with editorial assistance and comments by Vince Giuliano and Melody Winnig Initial  comments – by Vince Giuliano This blog entry is about thoroughly documented health and possible longevity benefits of meditation, quite apart from possible spiritual … Continue reading

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