The making of a dietary supplement – the long and short histories of it

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    By Vince Giuliano  June 3 2019 This blog entry tells the stories of how our new dietary supplement 4 Herb Synergy came into being.  As such, this blog entry tells two short histories: a universal history over more than … Continue reading

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INFLAMMATION PART 6: THE SCIENCE BEHIND THE 4 HERB SYNERGY DIETARY SUPPLEMENT

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Ancient plant wisdom meets nanotechnology By Vince Giuliano                                                                       May 28, 2019  This blog entry is concerned with a new dietary supplement that my colleagues I have sourced, called 4 Herb Synergy. It is concerned with the scientific considerations we have … Continue reading

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UPDATE ON LONGEVITY INTERVENTIONS – MAINLY PERSONAL

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“Start with the impossible. Proceed calmly towards the improbable. No worry, there are at least five exits.” —Father Daniel Berrigan By Vince Giuliano 4/11/19  This blog entry is about my ideas about my personal health and longevity. It is not … Continue reading

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AGING, CELL AND TISSUE REPAIR, RENEWAL AND REGENERATION, INFLAMMATION AND THE SASP

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By Vince Giuliano INTRODUCTION Many of us who have studied aging have long believed that, sooner or later we would discover keys to a long and healthy life via biological repair, renewal and regenerative processes. Based on what we have … Continue reading

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Inflammation Part 5: Inflammasomes – science of and disease implications

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By James P. Watson and Vince Giuliano Inflammasomes are multimeric self-assembling protein complexes within the cytosol of mammalian cells, pattern-recognizing components of the innate immune system.  They can be thought of as finely tuned alarm, triggering and amplifying systems that … Continue reading

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2018 meeting of the International Dose-Response Society

By Vince Giuliano As in previous years, I am posting this note regarding the forthcoming 2018 annual meeting of the International Dose-response Society.  It will be held as usual on the Campus of the University of Massachusetts in Amherst MA on April … Continue reading

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THE DOUBLE GENE KNOCKOUT BEHIND OUR OBESITY EPIDEMIC

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By James P Watson with assistance and added commentary by Vince Giuliano This is a story of how we got here to our obesity and metabolic disease epidemic.  Goes a bit back – around 30-40 million years – with another … Continue reading

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TALES OF NAD+ POWERPOINT PRESENTATION

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By Vince Giuliano Here is the PowerPoint presentation I made at the 3 rd Annual NAD Summit Conference on January 27 at 2 PM in San Diego. TALES OF NAD+  Just double click on the following link to download it. … Continue reading

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Part 2 of interventions that reduce all cause mortality (ACM) – Metformin

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by James P Watson and Vince Giuliano There is a community of self-experimenters who are taking the drug Metformin, not because they are diabetic or prediabetic, the FDA-approved reasons for prescribing the drug, but rather because they believe it probably … Continue reading

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Inflammation Part 4 – PCSK9 inhibition – Also Part 1 of interventions that reduce all cause mortality (ACM)

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By James P Watson with inputs and editorial assistance by Vince Giuliano I.  INTRODUCTION This is the fourth in what we expect will be seven or more blog posts concerned with chronic inflammation.  It relates to a recently discovered protein … Continue reading

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