Search Results for: DNA methylation

Prostate cancer – epigenetic factors, the role of Nrf2, cancer stem cells and actions of phytochemicals

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By Vince Giuliano There have been several important research findings in recent years relating to prostate cancer, ones that are transforming our views of the disease process and offering hopes for powerful new preventative and curative therapies.  This blog entry … Continue reading

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Epigenetic Mechanisms of Long-term Memory

By Victor We all know that we are able to store sensory experiences for later recall; in a very real sense, collection of memories acquired during life represents our personal identity.  However, the neuroscience of memory formation is still in … Continue reading

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More about Klotho – spinner of the thread of life

I published an introduction to the remarkable “anti-aging gene” Klotho in the October 2009 blog entryKlotho anti-aging gene in the news, and a September 2010 update Klotho, phosphates, cola drinks and longevity.  Since then in little more than a year, … Continue reading

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Mechanisms and Effects of Dietary Restriction

By Victor In 1934, researchers at Cornell University discovered that laboratory rats fed a severely restricted diet lived up to twice as long as those fed a regular diet.  Subsequent research has confirmed the health and longevity benefits of dietary … Continue reading

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Progress update on induced pluripotent stem cells

By Vince Giuliano The last few months have seen the continuation of an extraordinary pace of research related to induced pluripotent stem cells (iPSCs), a technology stream that has been widely heralded as key for organ regeneration, for regenerative medicine, … Continue reading

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Aging and the immune system – focus on naïve T-cells

By Vince Giuliano The human immune system provides our defenses against pathogens. This blog entry focuses on research on T-cells. a family of cells in the immune system.  The research is relevant to aging because it challenges the traditional view … Continue reading

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Aging as a genomic-epigenomic dance

By Vince Giuliano Much of what we observe in aging appears to come about through accumulated genomic damage, or through aging-related epigenomic mechanisms. This blog entry explores the relationship of genomics to epigenomics with respect to diseases and aging. Some … Continue reading

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Longevity of stem cells and the roles of stem cells in aging

By Vince Giuliano This blog entry is about somatic stem cells, the natural kind that reside in adult bodies, the factors that affect their health and longevity, the changes they undergo in the process of aging, and the roles they … Continue reading

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Update on induced pluripotent stem cells

By Vince Giuliano The last seven months have seen a great deal of research related to and induced pluripotent stem cells (iPSCs) and cell reprogramming. This blog post is devoted to some important perspectives that have emerged resulting from that … Continue reading

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The 2011 Bio-IT World Conference & Expo – On the way to Personalized Predictive Preventative Participatory Medicine

I introduced the PPPPM concept a year ago in a blog post Harnessing the engines of finance and commerce for life-extension.   I wrote that post just after having attended the 2010 version of the 2010 Bio-IT World Conference & Expo.  … Continue reading

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