Search Results for: nad world

Part 5 of the NAD world: the conflicting roles of NAMPT – inflammation or rescue? Also Part 1 on a new series on inflammation

By James P Watson with commentary and assistance by Vince Giuliano Introduction by Vince Giuliano This blog entry relates another important story of what goes on in the NAD world. This is also the first entry of what I expect … Continue reading

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Part 4 of the NAD world: the NQ01 gene, the Warburg effect, SIRT 1 and inflammation, and possible interventions

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By James P Watson with contributions and editorial assistance by Vince Giuliano This Part 4 blog entry goes even further into the extended NAD story, examining important subtopics: The ratio NAD+/NADH in cells and the body, which may be as … Continue reading

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NAD+ an emerging framework for life health and life extension — Part 2: Deeper into the NAD World, hopeful interventions

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By James P Watson with contributions and assistance by Vince Giuliano This is Part 2 of what will likely be a six-part series of blog entries related to the metabolic cofactor NAD+ and what goes on in the NAD World,  … Continue reading

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NAD+ an emerging framework for health and life extension — Part 1: The NAD World

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By Vince Giuliano with inputs from  James P. Watson Accelerated by the publication in December 2013 of a seminal paper by David Sinclair and his US and Australian colleagues(ref), there has been increasing interest and excitement about the prospects of … Continue reading

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TALES OF NAD+ POWERPOINT PRESENTATION

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By Vince Giuliano Here is the PowerPoint presentation I made at the 3 rd Annual NAD Summit Conference on January 27 at 2 PM in San Diego. TALES OF NAD+  Just double click on the following link to download it. … Continue reading

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30 Major Factors that Control SIRT1 Expression, SIRT1 Activity, and SIRT1-mediated Aging. Part 3 of the series NAD+ an emerging framework for health and life extension

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  By James P Watson with comments and editorial assistance by Vince Giuliano Introduction by Vince Giuliano: This is the third blog entry in the series NAD+ an emerging framework for health and life extension.  The first two entries were  … Continue reading

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The evolving narrative and social transformation of aging – Part 1: Important issues confronting the world associated with aging populations

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  By Vince Giuliano, Melody Winnig and Michael Giuliano How do you imagine growing old? Do you have the narrative that you dread becoming like the uncle who spent 5 years painfully wasting away with cancer? Or the mother who … Continue reading

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CHRONOBIOLOGY OF TISSUE REGENERATION

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By Vince Giuliano We have discussed important aspects of cell tissue regeneration in previous blog entries.  In particular see AGING, CELL AND TISSUE REPAIR, RENEWAL AND REGENERATION, INFLAMMATION AND THE SASP.  The present blog entry deals with circadian regulation; in … Continue reading

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Inflammation Part 8: Neurohormesis, neuroinflammatory diseases, and their treatment by mushroom substances (Section 2 of this discussion) Can a mushroom play an important role in the health and anti-aging picture? Recent research says Yes, and this blog entry tells another part of the story.

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REVIEW OF SCIENTIFIC ASPECTS RELATED TO NEUROINFLAMMATION: REACTIVE OXYGEN SPECIES, MITOCHONDRIAL FACTORS, INFLAMMASOMES, PPARs, METBOLIC PATHWAYS, SIRTs, DNA DAMAGE AND ROLES OF NRF2 AND NF-KB, AND ANOTHER MAGIC MUSHROOM, YUN-ZHI Continue reading

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Inflammation Part 7: Neurohormesis, neuroinflammatory diseases, and their treatment by mushroom substances (Section 1)

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Can a mushroom play an important role in the health and anti-aging picture?  Recent research says Yes, and this blog entry tells the story Current medical treatments for age-related neurological brain diseases like Alzheimer’s and Parkinson’s remain largely ineffective, despite … Continue reading

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