Search Results for: hormesis

Autophagy – the housekeeper in every cell that fights aging

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By James P Watson and Vince Giuliano Background and introduction There is a wide variety of genetic manipulations, pharmacologic manipulations, and nutrient manipulations that have been shown to alter lifespan in model organisms.  These include caloric restriction, “loss of function” … Continue reading

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Aging science wager challenges and prizes open to readers.

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Image source Frequent readers of this blog know that James P Watson (Jim) is a colleague and significant contributor to this blog.  Jim recently sent me an e-mail offering to make personal wager bets with me on two questions related … Continue reading

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The Prospects that Emerging Science Offers Us for Longer Healthy Lifespans

On March 25 2013, I gave a presentation “The Prospects that Emerging Science Offers Us for Longer Healthy Lifespans” as part of the Kopriva Science Seminar series at Montana State University.  Thanks in part to good newspaper publicity, The Hager … Continue reading

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Mitochondria Part 2: Mitochondrial Responses to Stress: Mitochondrial Signaling: Survival and Death Pathways

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Written by James Watson, with major contributions by Vince Giuliano Introduction – Mitochondrial Roles in the Cell This is the second part in a series of blog entries examining the roles of mitochondria in key biological activities.  For additional background … Continue reading

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Mitochondria in health and aging, and possibilities for life prolongation – Part 1:basics

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Written by Vince Giuliano, with major contributions by James P Watson This is the first of a series of blog entries examining the roles of mitochondria in key biological activities.  The goal of the series is to shed light on … Continue reading

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Plant polyphenols – six epigenetic knockout punches against cancers

Certain plant polyphenols not only exercise general positive health effects but also inhibit oncogenic transformation or the proliferation of cancer cells.  Or, they outright kill cancer cells.  Included are a substantial number of cancer-fighting plant polyphenols, some of which are … Continue reading

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The Hormetic Wild Animal “Zoo” and Their “Zookeepers”

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By James P Watson There are 2 “Mantras” Here in the Zoo – Hormesis and Nrf2 inducible Isoforms Preface – By Vince Giuliano I want to introduce and welcome James P Watson as a senior researcher and writer for this … Continue reading

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Editorial -Bridging the Great Divide

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     By Vince Giuliano There appears to be a Great Divide in the world when it comes to health, manifest most clearly in Western Countries and in the US in particular.  The divide is between two major paradigms of … Continue reading

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Adaptogens Part 1 – video blog

By Vince Giuliano This and the Part 2 blog entry are pursuant to one of the key themes of this blog –  the use of phyto substances to promote health and longevity.  Specifically, they are about adaptogens – certain plant … Continue reading

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The pivotal role of Nrf2. Part 2 – foods, phyto-substances and other substances that turn on Nrf2

By Vince Giuliano – updated Feb 8 and Feb 9, 2012 This is the second of three blog entries relating to the Nrf2 pathway.  The previous blog entry The pivotal role of Nrf2. Part 1 – a new view on … Continue reading

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