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By Vince Giuliano with important inputs from Gemini 3, ChatGPT 5 and Copilot 12-5-2025 PREFACE This is the Second Part of a two-part series of blog entries. The First Part MECHANISMS OF AGING AND INTERVENTIONS FOR LONGEVITY PART 1 … Continue reading
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PREFACE This is the first part of a two-part series of blog entries. It describes causal processes of human aging, as typical from birth to approximately 100 years of age. This description provides a comprehensive framework that is sufficient to … Continue reading
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Getting through ages 100 –125 alive and vibrantly healthily. By Vince Giuliano V7. 30 Mar 2025 This document outlines a personal longevity program aimed at my achieving health and vitality well beyond the age of 125, focusing on reversing aging … Continue reading
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By Vince Giuliano 9-27 -2023 Preface and a personal note In April of this year, I experienced a breakthrough in understanding human aging. This was a key event for me, coming after 15 years of full-time study and writing 600 … Continue reading
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By Vince Giuliano The causal chain of events leading to advanced human aging has only been clarified very recently. A key step in this causal chain is systemic inflammation leading to accelerated epigenetic aging. In reports of other researcher and … Continue reading
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By Vince Giuliano There are two distinct faces of life extension which are often confused, even by the best researchers working in the longevity field. This sometimes leads to paradoxical observations. I seek to clarify what these faces are in … Continue reading
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By A. Christopher Wikman, March 2022 INTRODUCTION Over the years, this weblog has brought to light, integrated and presented the science of aging and the healthy practices and interventions (see the post “PRACTICAL INTERVENTIONS FOR YOUNGING1.0 – Introduction to the … Continue reading
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By Vince Giuliano and Steve Buss As announced previously, on November 20 2021 Steve Buss and I were featured in an online Meetup of the London Futurist group. We focused on delivering a coherent presentation of our research reported in … Continue reading
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By Vince Giuliano and Steve Buss It is now generally accepted that the brain inhibits inflammation induced by an immune challenge resulting in the release of inflammatory cytokines or TNF in two main ways: biochemically, by activating the hypothalamic-pituitary-adrenal axis … Continue reading
