Search Results for: angiotensin

ACE and Angiotensin II: The “Double Agents” that Play Multiple Roles in the Molecular Story of Life

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By James P Watson, with editorial assist, a little rounding out and a few comments by Vince Giuliano Image source I am convinced that actions in the Renin-Angiotensin cascade can be a major cause of inflammation, aging, and cancer.  Exogenous antioxidants, … Continue reading

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Inflammation Part 5: Inflammasomes – science of and disease implications

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By James P. Watson and Vince Giuliano Inflammasomes are multimeric self-assembling protein complexes within the cytosol of mammalian cells, pattern-recognizing components of the innate immune system.  They can be thought of as finely tuned alarm, triggering and amplifying systems that … Continue reading

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Inflammation Part 4 – PCSK9 inhibition – Also Part 1 of interventions that reduce all cause mortality (ACM)

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By James P Watson with inputs and editorial assistance by Vince Giuliano I.  INTRODUCTION This is the fourth in what we expect will be seven or more blog posts concerned with chronic inflammation.  It relates to a recently discovered protein … Continue reading

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ON AGING

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By Vince Giuliano June 27 1017   Once in a while over the years I take a break from blog research and writing as I have done recently.  When I come back to the research and writing after such a … Continue reading

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The top 21Benefits of Meditation

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By James P Watson, with editorial assistance and comments by Vince Giuliano and Melody Winnig Initial  comments – by Vince Giuliano This blog entry is about thoroughly documented health and possible longevity benefits of meditation, quite apart from possible spiritual … Continue reading

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Part 4 of the NAD world: the NQ01 gene, the Warburg effect, SIRT 1 and inflammation, and possible interventions

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By James P Watson with contributions and editorial assistance by Vince Giuliano This Part 4 blog entry goes even further into the extended NAD story, examining important subtopics: The ratio NAD+/NADH in cells and the body, which may be as … Continue reading

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30 Major Factors that Control SIRT1 Expression, SIRT1 Activity, and SIRT1-mediated Aging. Part 3 of the series NAD+ an emerging framework for health and life extension

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  By James P Watson with comments and editorial assistance by Vince Giuliano Introduction by Vince Giuliano: This is the third blog entry in the series NAD+ an emerging framework for health and life extension.  The first two entries were  … Continue reading

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Digital health – health and fitness wearables, Part 3: Heart Rate Variability: Principles and Science and Practical Measuring Devices

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By James P Watson with contributions and editorial assistance by Vince Giuliano This is the third blog entry related to electronic wearable devices capable of making personal behavioral and physical parameter measurements that bear on health and wellness and likely … Continue reading

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NAD+ an emerging framework for life health and life extension — Part 2: Deeper into the NAD World, hopeful interventions

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By James P Watson with contributions and assistance by Vince Giuliano This is Part 2 of what will likely be a six-part series of blog entries related to the metabolic cofactor NAD+ and what goes on in the NAD World,  … Continue reading

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FIVE-YEAR PROGRESS REPORT ON MAJOR TRENDS IMPACTING ON LONGEVITY.

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By Vince Giuliano This is a progress report on the changing state of human longevity during the five-year lifespan of this blog.  It reviews major trends and forces impacting on our lifespans, both scientific and social.  Longevity can be viewed … Continue reading

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