Search Results for: inflammation

Inflammation Part 8: Neurohormesis, neuroinflammatory diseases, and their treatment by mushroom substances (Section 2 of this discussion) Can a mushroom play an important role in the health and anti-aging picture? Recent research says Yes, and this blog entry tells another part of the story.

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REVIEW OF SCIENTIFIC ASPECTS RELATED TO NEUROINFLAMMATION: REACTIVE OXYGEN SPECIES, MITOCHONDRIAL FACTORS, INFLAMMASOMES, PPARs, METBOLIC PATHWAYS, SIRTs, DNA DAMAGE AND ROLES OF NRF2 AND NF-KB, AND ANOTHER MAGIC MUSHROOM, YUN-ZHI Continue reading

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Inflammation Part 7: Neurohormesis, neuroinflammatory diseases, and their treatment by mushroom substances (Section 1)

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Can a mushroom play an important role in the health and anti-aging picture?  Recent research says Yes, and this blog entry tells the story Current medical treatments for age-related neurological brain diseases like Alzheimer’s and Parkinson’s remain largely ineffective, despite … Continue reading

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INFLAMMATION PART 6: THE SCIENCE BEHIND THE 4 HERB SYNERGY DIETARY SUPPLEMENT

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Ancient plant wisdom meets nanotechnology By Vince Giuliano                                                                       May 28, 2019  This blog entry is concerned with a new dietary supplement that my colleagues I have sourced, called 4 Herb Synergy. It is concerned with the scientific considerations we have … Continue reading

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AGING, CELL AND TISSUE REPAIR, RENEWAL AND REGENERATION, INFLAMMATION AND THE SASP

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By Vince Giuliano INTRODUCTION Many of us who have studied aging have long believed that, sooner or later we would discover keys to a long and healthy life via biological repair, renewal and regenerative processes. Based on what we have … Continue reading

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Inflammation Part 5: Inflammasomes – science of and disease implications

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By James P. Watson and Vince Giuliano Inflammasomes are multimeric self-assembling protein complexes within the cytosol of mammalian cells, pattern-recognizing components of the innate immune system.  They can be thought of as finely tuned alarm, triggering and amplifying systems that … Continue reading

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Inflammation Part 4 – PCSK9 inhibition – Also Part 1 of interventions that reduce all cause mortality (ACM)

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By James P Watson with inputs and editorial assistance by Vince Giuliano I.  INTRODUCTION This is the fourth in what we expect will be an open-ended series of blog posts concerned with chronic inflammation.  Parts 1-6 are already published  It … Continue reading

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Inflammation Part 3: resolving inflammation – resolvins, protectins, maresins and lipoxins

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By Vince Giuliano This Part 3 of the Inflammation series of blog entries is concerned with the all-important resolution phase of inflammation, how acute inflammation goes away under ideal conditions instead of hunkering down to lingering and dangerous chronic inflammation. … Continue reading

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Inflammation Part 2: The Tale of Three Stress Sensors and their Interactions: 1)Inflammation, 2)Genomic Instability (p53), and 3)Oxidative stress (Nrf2)

By James Watson, with contributions and editing by Vince Giuliano We promised a major series of blog entries related to inflammation back in May 2016.    We said we would do that through narrating a number of inter-related stories many of … Continue reading

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Part 5 of the NAD world: the conflicting roles of NAMPT – inflammation or rescue? Also Part 1 on a new series on inflammation

By James P Watson with commentary and assistance by Vince Giuliano Introduction by Vince Giuliano This blog entry relates another important story of what goes on in the NAD world. This is also the first entry of what I expect … Continue reading

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Part 4 of the NAD world: the NQ01 gene, the Warburg effect, SIRT 1 and inflammation, and possible interventions

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By James P Watson with contributions and editorial assistance by Vince Giuliano This Part 4 blog entry goes even further into the extended NAD story, examining important subtopics: The ratio NAD+/NADH in cells and the body, which may be as … Continue reading

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