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By Vince Giuliano and Steve Buss It is now generally accepted that the brain inhibits inflammation induced by an immune challenge resulting in the release of inflammatory cytokines or TNF in two main ways: biochemically, by activating the hypothalamic-pituitary-adrenal axis … Continue reading
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REVIEW OF SCIENTIFIC ASPECTS RELATED TO NEUROINFLAMMATION: REACTIVE OXYGEN SPECIES, MITOCHONDRIAL FACTORS, INFLAMMASOMES, PPARs, METBOLIC PATHWAYS, SIRTs, DNA DAMAGE AND ROLES OF NRF2 AND NF-KB, AND ANOTHER MAGIC MUSHROOM, YUN-ZHI Continue reading
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Can a mushroom play an important role in the health and anti-aging picture? Recent research says Yes, and this blog entry tells the story Current medical treatments for age-related neurological brain diseases like Alzheimer’s and Parkinson’s remain largely ineffective, despite … Continue reading
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Ancient plant wisdom meets nanotechnology By Vince Giuliano May 28, 2019 This blog entry is concerned with a new dietary supplement that my colleagues I have sourced, called 4 Herb Synergy. It is concerned with the scientific considerations we have … Continue reading
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By Vince Giuliano INTRODUCTION Many of us who have studied aging have long believed that, sooner or later we would discover keys to a long and healthy life via biological repair, renewal and regenerative processes. Based on what we have … Continue reading
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By James P. Watson and Vince Giuliano Inflammasomes are multimeric self-assembling protein complexes within the cytosol of mammalian cells, pattern-recognizing components of the innate immune system. They can be thought of as finely tuned alarm, triggering and amplifying systems that … Continue reading
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By James P Watson with inputs and editorial assistance by Vince Giuliano I. INTRODUCTION This is the fourth in what we expect will be an open-ended series of blog posts concerned with chronic inflammation. Parts 1-6 are already published It … Continue reading
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By Vince Giuliano This Part 3 of the Inflammation series of blog entries is concerned with the all-important resolution phase of inflammation, how acute inflammation goes away under ideal conditions instead of hunkering down to lingering and dangerous chronic inflammation. … Continue reading
By James Watson, with contributions and editing by Vince Giuliano We promised a major series of blog entries related to inflammation back in May 2016. We said we would do that through narrating a number of inter-related stories many of … Continue reading
By James P Watson with commentary and assistance by Vince Giuliano Introduction by Vince Giuliano This blog entry relates another important story of what goes on in the NAD world. This is also the first entry of what I expect … Continue reading
